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Koźmiński P, Gawęda W, Rzewuska M, et al. Physicochemical and Biological Study of . Tomography. 2021;7(4):829-842doi: 10.3390/tomography7040070.
Koźmiński, P., Gawęda, W., Rzewuska, M., Kopatys, A., Kujda, S., Dudek, M. K., Halik, P. K., Królicki, L., & Gniazdowska, E. (2021). Physicochemical and Biological Study of . Tomography (Ann Arbor, Mich.), 7(4), 829-842. https://doi.org/10.3390/tomography7040070
Koźmiński, Przemysław, et al. "Physicochemical and Biological Study of ." Tomography (Ann Arbor, Mich.) vol. 7,4 (2021): 829-842. doi: https://doi.org/10.3390/tomography7040070
Koźmiński P, Gawęda W, Rzewuska M, Kopatys A, Kujda S, Dudek MK, Halik PK, Królicki L, Gniazdowska E. Physicochemical and Biological Study of . Tomography. 2021 Dec 01;7(4):829-842. doi: 10.3390/tomography7040070. PMID: 34941642; PMCID: PMC8707861.
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Tomography. 2021 Dec 01;7(4):829-842. doi: 10.3390/tomography7040070.

Physicochemical and Biological Study of .

Tomography (Ann Arbor, Mich.)

Przemysław Koźmiński, Weronika Gawęda, Magdalena Rzewuska, Agata Kopatys, Szymon Kujda, Marta K Dudek, Paweł Krzysztof Halik, Leszek Królicki, Ewa Gniazdowska

Affiliations

  1. Centre of Radiochemistry and Nuclear Chemistry, Institute of Nuclear Chemistry and Technology, Dorodna 16, 03-195 Warsaw, Poland.
  2. Institute of Veterinary Medicine, Department of Preclinical Sciences, Division of Microbiology, Warsaw University of Life Sciences-SGGW, Ciszewskiego 8, 02-786 Warsaw, Poland.
  3. Department of Nuclear Medicine, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland.
  4. Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Sienkiewicza 112, 90-363 Lodz, Poland.

PMID: 34941642 PMCID: PMC8707861 DOI: 10.3390/tomography7040070

Abstract

This paper presents the application of ciprofloxacin as a biologically active molecule (vector) for delivering diagnostic radiopharmaceuticals to the sites of bacterial infection. Ciprofloxacin-based radioconjugates containing technetium-99m or gallium-68 radionuclides were synthesised, and their physicochemical (stability, lipophilicity) and biological (binding study to

Keywords: bacterial infection; ciprofloxacin; diabetic foot; gallium-68; radiopharmaceutical; technetium-99m

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