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Front Oncol. 2021 Dec 07;11:730854. doi: 10.3389/fonc.2021.730854. eCollection 2021.

Comprehensive Imaging Characterization of Colorectal Liver Metastases.

Frontiers in oncology

Drew Maclean, Maria Tsakok, Fergus Gleeson, David J Breen, Robert Goldin, John Primrose, Adrian Harris, James Franklin

Affiliations

  1. Department of Radiology, University Hospital Southampton, Southampton, United Kingdom.
  2. Department of Medical Imaging, Bournemouth University, Bournemouth, United Kingdom.
  3. Department of Radiology, Oxford University Hospitals, Oxford, United Kingdom.
  4. Department of Oncology, Oxford University, Oxford, United Kingdom.
  5. Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.
  6. Department of Surgery, University Hospital Southampton, Southampton, United Kingdom.
  7. Academic Unit of Cancer Sciences, University of Southampton, Southampton, United Kingdom.

PMID: 34950575 PMCID: PMC8688250 DOI: 10.3389/fonc.2021.730854

Abstract

Colorectal liver metastases (CRLM) have heterogenous histopathological and immunohistochemical phenotypes, which are associated with variable responses to treatment and outcomes. However, this information is usually only available after resection, and therefore of limited value in treatment planning. Improved techniques for

Copyright © 2021 Maclean, Tsakok, Gleeson, Breen, Goldin, Primrose, Harris and Franklin.

Keywords: MRI; colorectal (colon) cancer; computed tomography; liver; metastasis; radiomic biomarkers

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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