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Britto-Júnior J, Ribeiro A, Ximenes L, et al. Alpha1-adrenergic antagonists block 6-nitrodopamine contractions on the rat isolated epididymal vas deferens. Eur J Pharmacol. 2021;174716doi: 10.1016/j.ejphar.2021.174716.
Britto-Júnior, J., Ribeiro, A., Ximenes, L., Lima, A. T., Jacintho, F. F., Fregonesi, A., Mónica, F. Z., Antunes, E., & De Nucci, G. (2021). Alpha1-adrenergic antagonists block 6-nitrodopamine contractions on the rat isolated epididymal vas deferens. European journal of pharmacology, 174716. https://doi.org/10.1016/j.ejphar.2021.174716
Britto-Júnior, José, et al. "Alpha1-adrenergic antagonists block 6-nitrodopamine contractions on the rat isolated epididymal vas deferens." European journal of pharmacology vol. (2021): 174716. doi: https://doi.org/10.1016/j.ejphar.2021.174716
Britto-Júnior J, Ribeiro A, Ximenes L, Lima AT, Jacintho FF, Fregonesi A, Mónica FZ, Antunes E, De Nucci G. Alpha1-adrenergic antagonists block 6-nitrodopamine contractions on the rat isolated epididymal vas deferens. Eur J Pharmacol. 2021 Dec 21;174716. doi: 10.1016/j.ejphar.2021.174716. Epub 2021 Dec 21. PMID: 34951979.
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Eur J Pharmacol. 2021 Dec 21;174716. doi: 10.1016/j.ejphar.2021.174716. Epub 2021 Dec 21.

Alpha1-adrenergic antagonists block 6-nitrodopamine contractions on the rat isolated epididymal vas deferens.

European journal of pharmacology

José Britto-Júnior, André Ribeiro, Luiz Ximenes, Antonio Tiago Lima, Felipe Fernandes Jacintho, Adriano Fregonesi, Fabíola Z Mónica, Edson Antunes, Gilberto De Nucci

Affiliations

  1. Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas, SP, Brazil. Electronic address: [email protected].
  2. Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas, SP, Brazil.
  3. Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas, SP, Brazil; Department of Pharmacology, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, SP, Brazil; Department of Pharmacology, Faculty of Medicine, São Leopoldo Mandic, Campinas, SP, Brazil; Brazil University, Fernandópolis, SP, Brazil.

PMID: 34951979 DOI: 10.1016/j.ejphar.2021.174716

Abstract

6-nitrodopamine (6-ND) is released from rat isolated vas deferens and modulates electrical-field stimulation (EFS) contractions of the rat isolated epididymal vas deferens (RIEVD) via a specific receptor which is blocked by tricyclic antidepressants. Here, the effects of selective α

Copyright © 2021. Published by Elsevier B.V.

Keywords: EFS; Idazoxan; L-NAME; Nitrocatecholamines; Premature ejaculation

Conflict of interest statement

Declaration of competing interest The authors declare no competing or financial interests.

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