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Schwarz KG, Pereyra KV, Toledo C, et al. Effects of enriched-potassium diet on cardiorespiratory outcomes in experimental non-ischemic chronic heart failure. Biol Res. 2021;54(1):43doi: 10.1186/s40659-021-00365-z.
Schwarz, K. G., Pereyra, K. V., Toledo, C., Andrade, D. C., Díaz, H. S., Díaz-Jara, E., Ortolani, D., Rios-Gallardo, A., Arias, P., Las Heras, A., Vera, I., Ortiz, F. C., Inestrosa, N. C., Vio, C. P., & Del Rio, R. (2021). Effects of enriched-potassium diet on cardiorespiratory outcomes in experimental non-ischemic chronic heart failure. Biological research, 54(1), 43. https://doi.org/10.1186/s40659-021-00365-z
Schwarz, Karla G, et al. "Effects of enriched-potassium diet on cardiorespiratory outcomes in experimental non-ischemic chronic heart failure." Biological research vol. 54,1 (2021): 43. doi: https://doi.org/10.1186/s40659-021-00365-z
Schwarz KG, Pereyra KV, Toledo C, Andrade DC, Díaz HS, Díaz-Jara E, Ortolani D, Rios-Gallardo A, Arias P, Las Heras A, Vera I, Ortiz FC, Inestrosa NC, Vio CP, Del Rio R. Effects of enriched-potassium diet on cardiorespiratory outcomes in experimental non-ischemic chronic heart failure. Biol Res. 2021 Dec 24;54(1):43. doi: 10.1186/s40659-021-00365-z. PMID: 34952651.
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Biol Res. 2021 Dec 24;54(1):43. doi: 10.1186/s40659-021-00365-z.

Effects of enriched-potassium diet on cardiorespiratory outcomes in experimental non-ischemic chronic heart failure.

Biological research

Karla G Schwarz, Katherin V Pereyra, Camilo Toledo, David C Andrade, Hugo S Díaz, Esteban Díaz-Jara, Domiziana Ortolani, Angélica Rios-Gallardo, Paulina Arias, Alexandra Las Heras, Ignacio Vera, Fernando C Ortiz, Nibaldo C Inestrosa, Carlos P Vio, Rodrigo Del Rio

Affiliations

  1. Laboratory of Cardiorespiratory Control, Department of Physiology, Pontificia Universidad Católica de Chile, Santiago, Chile.
  2. Centro de Excelencia en Biomedicina de Magallanes (CEBIMA), Universidad de Magallanes, Punta Arenas, Chile.
  3. Centro de Fisiología y Medicina de Altura, Departamento Biomédico, Facultad de Ciencias de la Salud, Universidad de Antofagasta, Antofagasta, Chile.
  4. Mechanisms of Myelin Formation and Repair Laboratory, Instituto de Ciencias Biomédicas, Facultad de Ciencias de Salud, Universidad Autónoma de Chile, Santiago, Chile.
  5. Centro de Envejecimiento y Regeneración (CARE), Pontificia Universidad Católica de Chile, Santiago, Chile.
  6. Facultad de Medicina y Ciencia, Universidad San Sebastián, Santiago, Chile.
  7. Laboratory of Cardiorespiratory Control, Department of Physiology, Pontificia Universidad Católica de Chile, Santiago, Chile. [email protected].
  8. Centro de Excelencia en Biomedicina de Magallanes (CEBIMA), Universidad de Magallanes, Punta Arenas, Chile. [email protected].
  9. Centro de Envejecimiento y Regeneración (CARE), Pontificia Universidad Católica de Chile, Santiago, Chile. [email protected].

PMID: 34952651 DOI: 10.1186/s40659-021-00365-z

Abstract

BACKGROUND: Chronic heart failure (CHF) is a global health problem. Increased sympathetic outflow, cardiac arrhythmogenesis and irregular breathing patterns have all been associated with poor outcomes in CHF. Several studies showed that activation of the renin-angiotensin system (RAS) play a key role in CHF pathophysiology. Interestingly, potassium (K

METHODS: Adult male Sprague-Dawley rats underwent volume overload to induce non-ischemic CHF. Animals were randomly allocated to normal chow diet (CHF group) or supplemented K

RESULTS: Compared to normal chow diet, K

CONCLUSION: Our findings support that dietary K

© 2021. The Author(s).

Keywords: Autonomic imbalance; Breathing disorders; Chemoreflex function; Heart failure; Potassium supplemented diet

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