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Wiegand C, Hipler UC, Elsner P, et al. Keratinocyte and Fibroblast Wound Healing In Vitro Is Repressed by Non-Optimal Conditions but the Reparative Potential Can Be Improved by Water-Filtered Infrared A. Biomedicines. 2021;9(12)doi: 10.3390/biomedicines9121802.
Wiegand, C., Hipler, U. C., Elsner, P., & Tittelbach, J. (2021). Keratinocyte and Fibroblast Wound Healing In Vitro Is Repressed by Non-Optimal Conditions but the Reparative Potential Can Be Improved by Water-Filtered Infrared A. Biomedicines, 9(12), . https://doi.org/10.3390/biomedicines9121802
Wiegand, Cornelia, et al. "Keratinocyte and Fibroblast Wound Healing In Vitro Is Repressed by Non-Optimal Conditions but the Reparative Potential Can Be Improved by Water-Filtered Infrared A." Biomedicines vol. 9,12 (2021). doi: https://doi.org/10.3390/biomedicines9121802
Wiegand C, Hipler UC, Elsner P, Tittelbach J. Keratinocyte and Fibroblast Wound Healing In Vitro Is Repressed by Non-Optimal Conditions but the Reparative Potential Can Be Improved by Water-Filtered Infrared A. Biomedicines. 2021 Nov 30;9(12). doi: 10.3390/biomedicines9121802. PMID: 34944618.
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Biomedicines. 2021 Nov 30;9(12). doi: 10.3390/biomedicines9121802.

Keratinocyte and Fibroblast Wound Healing In Vitro Is Repressed by Non-Optimal Conditions but the Reparative Potential Can Be Improved by Water-Filtered Infrared A.

Biomedicines

Cornelia Wiegand, Uta-Christina Hipler, Peter Elsner, Jörg Tittelbach

Affiliations

  1. Department of Dermatology, University Hospital Jena, Erfurter Str. 35, 07743 Jena, Germany.

PMID: 34944618 DOI: 10.3390/biomedicines9121802

Abstract

It is a general goal to improve wound healing, especially of chronic wounds. As light therapy has gained increasing attention, the positive influence on healing progression of water-filtered infrared A (wIRA), a special form of thermal radiation, has been investigated and compared to the detrimental effects of UV-B irradiation on wound closure in vitro. Models of keratinocyte and fibroblast scratches help to elucidate effects on epithelial and dermal healing. This study further used the simulation of non-optimal settings such as

Keywords: UV-B; collagen; desmoglein; fibroblast; heat shock protein; keratinocyte; pro-inflammatory cytokines; scratch assay; wIRA (water-filtered infrared A); wound healing

Publication Types

Grant support