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Eur J Mass Spectrom (Chichester). 2021 Dec 24;14690667211069033. doi: 10.1177/14690667211069033. Epub 2021 Dec 24.

Elucidating the Fragmentation Mechanism of Protonated Lewis A Trisaccharide using MS.

European journal of mass spectrometry (Chichester, England)

Volker Iwan, Jürgen Grotemeyer

Affiliations

  1. Institute of Physical Chemistry, 9179Christian-Albrechts-University Kiel, Kiel, Germany.

PMID: 34951325 DOI: 10.1177/14690667211069033

Abstract

Lewis blood group antigens are a prominent example of isomeric oligosaccharides with biological activity. Understanding the fragmentation mechanism in the gas phase is essential for their identification and assignment by mass spectrometric methods such as ESI-MS. In this work, the [M + H]

Keywords: CID; ESI; FT-ICR; Lewis A trisaccharide; Oligosaccharides; mass spectrometry

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