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Buckley C, Wang CY, Chatfield MD, et al. The impact of COVID-19 epidemic phase and changes in mean viral loads: implications for SARS-CoV-2 testing strategies. Diagn Microbiol Infect Dis. 2021;102(3):115598doi: 10.1016/j.diagmicrobio.2021.115598.
Buckley, C., Wang, C. Y., Chatfield, M. D., Bletchly, C., Harris, P., & Whiley, D. (2021). The impact of COVID-19 epidemic phase and changes in mean viral loads: implications for SARS-CoV-2 testing strategies. Diagnostic microbiology and infectious disease, 102(3), 115598. https://doi.org/10.1016/j.diagmicrobio.2021.115598
Buckley, Cameron, et al. "The impact of COVID-19 epidemic phase and changes in mean viral loads: implications for SARS-CoV-2 testing strategies." Diagnostic microbiology and infectious disease vol. 102,3 (2021): 115598. doi: https://doi.org/10.1016/j.diagmicrobio.2021.115598
Buckley C, Wang CY, Chatfield MD, Bletchly C, Harris P, Whiley D. The impact of COVID-19 epidemic phase and changes in mean viral loads: implications for SARS-CoV-2 testing strategies. Diagn Microbiol Infect Dis. 2021 Nov 19;102(3):115598. doi: 10.1016/j.diagmicrobio.2021.115598. Epub 2021 Nov 19. PMID: 34883385; PMCID: PMC8603442.
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Diagn Microbiol Infect Dis. 2021 Nov 19;102(3):115598. doi: 10.1016/j.diagmicrobio.2021.115598. Epub 2021 Nov 19.

The impact of COVID-19 epidemic phase and changes in mean viral loads: implications for SARS-CoV-2 testing strategies.

Diagnostic microbiology and infectious disease

Cameron Buckley, Claire Yt Wang, Mark D Chatfield, Cheryl Bletchly, Patrick Harris, David Whiley

Affiliations

  1. Faculty of Medicine, The University of Queensland Centre for Clinical Research, The University of Queensland, Brisbane, Queensland, Australia; Pathology Queensland Central Laboratory, Brisbane, Queensland, Australia.
  2. Pathology Queensland Central Laboratory, Brisbane, Queensland, Australia; Centre for Children's Health Research, Children's Health Queensland, Brisbane, Queensland, Australia.
  3. Faculty of Medicine, The University of Queensland Centre for Clinical Research, The University of Queensland, Brisbane, Queensland, Australia.
  4. Pathology Queensland Central Laboratory, Brisbane, Queensland, Australia.
  5. Faculty of Medicine, The University of Queensland Centre for Clinical Research, The University of Queensland, Brisbane, Queensland, Australia; Pathology Queensland Central Laboratory, Brisbane, Queensland, Australia. Electronic address: [email protected].

PMID: 34883385 PMCID: PMC8603442 DOI: 10.1016/j.diagmicrobio.2021.115598

Abstract

The sensitivity of SARS-CoV-2 diagnostic tests is inherently linked to viral load. We explored whether average viral loads changed at a population level in Queensland, Australia during the early phase of the pandemic. RT-PCR threshold cycle (C

Copyright © 2021 Elsevier Inc. All rights reserved.

Keywords: SARS-CoV-2; diagnosis; phase; viral load

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