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Alfhili MA, Aljuraiban GS. Lauric Acid, a Dietary Saturated Medium-Chain Fatty Acid, Elicits Calcium-Dependent Eryptosis. Cells. 2021;10(12)doi: 10.3390/cells10123388.
Alfhili, M. A., & Aljuraiban, G. S. (2021). Lauric Acid, a Dietary Saturated Medium-Chain Fatty Acid, Elicits Calcium-Dependent Eryptosis. Cells, 10(12), . https://doi.org/10.3390/cells10123388
Alfhili, Mohammad A, and Aljuraiban, Ghadeer S. "Lauric Acid, a Dietary Saturated Medium-Chain Fatty Acid, Elicits Calcium-Dependent Eryptosis." Cells vol. 10,12 (2021). doi: https://doi.org/10.3390/cells10123388
Alfhili MA, Aljuraiban GS. Lauric Acid, a Dietary Saturated Medium-Chain Fatty Acid, Elicits Calcium-Dependent Eryptosis. Cells. 2021 Dec 01;10(12). doi: 10.3390/cells10123388. PMID: 34943896.
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Cells. 2021 Dec 01;10(12). doi: 10.3390/cells10123388.

Lauric Acid, a Dietary Saturated Medium-Chain Fatty Acid, Elicits Calcium-Dependent Eryptosis.

Cells

Mohammad A Alfhili, Ghadeer S Aljuraiban

Affiliations

  1. Chair of Medical and Molecular Genetics Research, Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 12372, Saudi Arabia.
  2. Department of Community Health Sciences, King Saud University, Riyadh 12372, Saudi Arabia.

PMID: 34943896 DOI: 10.3390/cells10123388

Abstract

Cardiovascular diseases (CVD) are a leading cause of mortality worldwide, and dietary habits represent a major risk factor for dyslipidemia; a hallmark of CVD. Saturated fatty acids contribute to CVD by aggravating dyslipidemia, and, in particular, lauric acid (LA) raises circulating cholesterol levels. The role of red blood cells (RBCs) in CVD is increasingly being appreciated, and eryptosis has recently been identified as a novel mechanism in CVD. However, the effect of LA on RBC physiology has not been thoroughly investigated. RBCs were isolated from heparin-anticoagulated whole blood (WB) and exposed to 50-250 μM of LA for 24 h at 37 °C. Hemoglobin was photometrically examined as an indicator of hemolysis, whereas eryptosis was assessed by Annexin V-FITC for phosphatidylserine (PS) exposure, Fluo4/AM for Ca

Keywords: calcium; cardiovascular disease; eryptosis; hemolysis; lauric acid

References

  1. Am Fam Physician. 2004 Jun 1;69(11):2599-606 - PubMed
  2. Mol Med Rep. 2016 Mar;13(3):2606-12 - PubMed
  3. J Inherit Metab Dis. 1993;16(4):648-69 - PubMed
  4. QJM. 2006 Dec;99(12):851-62 - PubMed
  5. Am J Clin Nutr. 2020 Dec 10;112(6):1642-1652 - PubMed
  6. Annu Rev Nutr. 1996;16:33-50 - PubMed
  7. Chemotherapy. 2013;59(3):214-24 - PubMed
  8. Prog Lipid Res. 2013 Oct;52(4):354-73 - PubMed
  9. Eur Heart J. 2007 Nov;28(22):2763-9 - PubMed
  10. Nephrol Dial Transplant. 2000;15 Suppl 3:14-8 - PubMed
  11. Trends Cardiovasc Med. 2001 Apr-May;11(3-4):162-5 - PubMed
  12. Cell Signal. 2012 May;24(5):981-90 - PubMed
  13. Biochim Biophys Acta. 1969;183(3):499-511 - PubMed
  14. Nutrients. 2019 Aug 28;11(9): - PubMed
  15. Atherosclerosis. 1999 Jun;144(2):285-301 - PubMed
  16. Int J Biochem. 1986;18(9):771-5 - PubMed
  17. Eur Heart J. 2007 Nov;28(22):2699-700 - PubMed
  18. Cardiovasc Res. 2021 Jul 06;: - PubMed
  19. Arch Pharm Res. 2013 Jul;36(7):912-7 - PubMed
  20. Eur Heart J. 2000 Apr;21(7):515-20 - PubMed
  21. Oxid Med Cell Longev. 2020 May 14;2020:5732956 - PubMed
  22. J Am Diet Assoc. 2008 Feb;108(2):287-331 - PubMed
  23. Eur Heart J. 2000 Oct;21(19):1614-20 - PubMed
  24. Am J Clin Nutr. 1994 Feb;59(2):371-7 - PubMed
  25. Cell Physiol Biochem. 2017;43(2):431-444 - PubMed
  26. Clin Nutr. 2004 Aug;23(4):721-32 - PubMed
  27. Biomed Res Int. 2018 Jan 3;2018:9405617 - PubMed
  28. Circulation. 2002 Mar 26;105(12):1485-90 - PubMed
  29. Circ Heart Fail. 2013 Sep 1;6(5):964-9 - PubMed
  30. Toxicon. 2021 Aug;199:41-48 - PubMed
  31. Oxid Med Cell Longev. 2019 May 9;2019:5028181 - PubMed
  32. Arterioscler Thromb. 1991 Nov-Dec;11(6):1700-11 - PubMed
  33. Early Hum Dev. 2001 Nov;65 Suppl:S95-S101 - PubMed
  34. Biology (Basel). 2020 Oct 22;9(11): - PubMed
  35. J Food Biochem. 2021 Apr;45(4):e13710 - PubMed
  36. BMJ. 2018 Jun 13;361:k2139 - PubMed
  37. Isr Med Assoc J. 2004 Jan;6(1):16-8 - PubMed
  38. Cell Physiol Biochem. 2016;39(5):1977-2000 - PubMed
  39. BMJ. 2019 Jul 3;366:l4137 - PubMed
  40. Am J Clin Nutr. 1992 Nov;56(5):895-8 - PubMed
  41. Front Physiol. 2021 Feb 23;12:638027 - PubMed
  42. Ann Transl Med. 2017 Aug;5(16):326 - PubMed
  43. Methods Mol Biol. 2021;2326:155-165 - PubMed
  44. Free Radic Biol Med. 1999 Nov;27(9-10):916-21 - PubMed
  45. J Nutr. 1995 Mar;125(3):466-73 - PubMed
  46. Biomolecules. 2020 Jul 30;10(8): - PubMed
  47. N Engl J Med. 1991 Aug 8;325(6):373-81 - PubMed
  48. J Cell Mol Med. 2010 Apr;14(4):840-60 - PubMed
  49. J Lab Physicians. 2020 Dec;12(4):239-243 - PubMed
  50. Rejuvenation Res. 2013 Jun;16(3):179-84 - PubMed
  51. Am J Epidemiol. 2003 Nov 1;158(9):844-51 - PubMed
  52. Nutrients. 2019 Sep 04;11(9): - PubMed
  53. Cardiovasc Res. 2013 Apr 1;98(1):37-46 - PubMed
  54. Clin Sci (Lond). 2006 Nov;111(5):307-17 - PubMed
  55. Biol Pharm Bull. 2021 Mar 1;44(3):372-378 - PubMed
  56. Kardiol Pol. 2018;76(4):713-722 - PubMed
  57. Int J Occup Med Environ Health. 2021 Aug 30;: - PubMed
  58. Biochim Biophys Acta. 1975 Nov 17;413(1):65-78 - PubMed
  59. J Am Coll Cardiol. 2005 Jun 7;45(11):1802-6 - PubMed
  60. JPEN J Parenter Enteral Nutr. 2000 Mar-Apr;24(2):113-8 - PubMed
  61. Toxicol Appl Pharmacol. 2019 May 1;370:36-43 - PubMed
  62. Am J Clin Nutr. 2018 Nov 1;108(5):1069-1091 - PubMed
  63. Biochem Biophys Res Commun. 2005 Dec 23;338(3):1368-73 - PubMed
  64. Am J Cardiol. 2003 Feb 6;91(3A):7A-11A - PubMed
  65. Essays Biochem. 2015;59:43-69 - PubMed
  66. Circulation. 1999 Feb 2;99(4):591-5 - PubMed
  67. Antioxid Redox Signal. 2006 Jul-Aug;8(7-8):1183-92 - PubMed
  68. J Nutr. 2001 Feb;131(2):242-5 - PubMed
  69. Blood. 2005 Dec 15;106(13):4034-42 - PubMed
  70. BMC Cardiovasc Disord. 2009 Nov 12;9:51 - PubMed
  71. Antioxid Redox Signal. 2017 Nov 10;27(14):1083-1124 - PubMed
  72. Sensors (Basel). 2011;11(2):1744-55 - PubMed
  73. Cell Death Discov. 2017 Sep 18;3:17063 - PubMed
  74. Med Hypotheses. 2004;62(6):966-9 - PubMed
  75. Diabetes Care. 2011 Jan;34(1):162-7 - PubMed
  76. Am J Clin Nutr. 2003 May;77(5):1146-55 - PubMed
  77. Hum Exp Toxicol. 2019 Jul;38(7):753-761 - PubMed
  78. Chem Biol Interact. 1991;79(3):335-47 - PubMed
  79. Toxicol In Vitro. 2002 Dec;16(6):741-7 - PubMed
  80. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Apr 15;1019:178-90 - PubMed
  81. Cell Biochem Funct. 1998 Dec;16(4):253-9 - PubMed
  82. Am J Clin Nutr. 1996 Jun;63(6):897-903 - PubMed
  83. J Korean Med Sci. 2016 Jan;31(1):98-105 - PubMed
  84. Eur J Clin Invest. 2015 Dec;45(12):1316-24 - PubMed
  85. Chemosphere. 2019 Aug;229:103-111 - PubMed
  86. J Chemother. 2021 Aug 19;:1-11 - PubMed
  87. J Food Biochem. 2021 Nov;45(11):e13977 - PubMed
  88. Circulation. 2021 Feb 23;143(8):e254-e743 - PubMed
  89. Am J Clin Nutr. 2011 Sep;94(3):847-53 - PubMed
  90. Food Chem Toxicol. 1995 Jul;33(7):601-17 - PubMed
  91. J Am Coll Cardiol. 2020 Dec 22;76(25):2982-3021 - PubMed

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