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Aries ML, Cloninger MJ. NMR Hydrophilic Metabolomic Analysis of Bacterial Resistance Pathways Using Multivalent Antimicrobials with Challenged and Unchallenged Wild Type and Mutated Gram-Positive Bacteria. Int J Mol Sci. 2021;22(24)doi: 10.3390/ijms222413606.
Aries, M. L., & Cloninger, M. J. (2021). NMR Hydrophilic Metabolomic Analysis of Bacterial Resistance Pathways Using Multivalent Antimicrobials with Challenged and Unchallenged Wild Type and Mutated Gram-Positive Bacteria. International journal of molecular sciences, 22(24), . https://doi.org/10.3390/ijms222413606
Aries, Michelle L, and Cloninger, Mary J. "NMR Hydrophilic Metabolomic Analysis of Bacterial Resistance Pathways Using Multivalent Antimicrobials with Challenged and Unchallenged Wild Type and Mutated Gram-Positive Bacteria." International journal of molecular sciences vol. 22,24 (2021). doi: https://doi.org/10.3390/ijms222413606
Aries ML, Cloninger MJ. NMR Hydrophilic Metabolomic Analysis of Bacterial Resistance Pathways Using Multivalent Antimicrobials with Challenged and Unchallenged Wild Type and Mutated Gram-Positive Bacteria. Int J Mol Sci. 2021 Dec 19;22(24). doi: 10.3390/ijms222413606. PMID: 34948402; PMCID: PMC8715671.
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Int J Mol Sci. 2021 Dec 19;22(24). doi: 10.3390/ijms222413606.

NMR Hydrophilic Metabolomic Analysis of Bacterial Resistance Pathways Using Multivalent Antimicrobials with Challenged and Unchallenged Wild Type and Mutated Gram-Positive Bacteria.

International journal of molecular sciences

Michelle L Aries, Mary J Cloninger

Affiliations

  1. Department of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717, USA.

PMID: 34948402 PMCID: PMC8715671 DOI: 10.3390/ijms222413606

Abstract

Multivalent membrane disruptors are a relatively new antimicrobial scaffold that are difficult for bacteria to develop resistance to and can act on both Gram-positive and Gram-negative bacteria. Proton Nuclear Magnetic Resonance (

Keywords: Bacillus cereus; DABCO; Gram-positive bacteria; antibiotic resistance; dendrimers; membrane disruption; metabolomics; nuclear magnetic resonance; quaternary ammonium compounds

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