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Turk J Ophthalmol. 2021 Dec 28;51(6):381-392. doi: 10.4274/tjo.galenos.2021.28227.

Evolving Techniques and Indications of Descemet Membrane Endothelial Keratoplasty.

Turkish journal of ophthalmology

Özlem Evren Kemer, Emine Esra Karaca, Silke Oellerich, Gerrit Melles

Affiliations

  1. University of Health Sciences Turkey, Ankara City Hospital, Ankara, Turkey.
  2. Netherlands Institute For Innovative Ocular Surgery (NIIOS), Rotterdam, The Netherlands.

PMID: 34963266 DOI: 10.4274/tjo.galenos.2021.28227

Abstract

Endothelial keratoplasty has replaced traditional penetrating keratoplasty for the treatment of corneal endothelial dysfunction. It offers faster, more predictable, stable visual recovery and low rejection rates while the surgery itself is less invasive. Descemet membrane endothelial keratoplasty (DMEK) is currently the gold standard for the treatment of Fuchs endothelial dystrophy, bullous keratopathy, and corneal edema after cataract surgery. Its favorable long-term outcomes are increasingly reported by large study groups. This review summarizes the current literature on new DMEK techniques, including size and shape modifications, new graft delivery techniques, and surgical pearls for challenging cases like eyes with glaucoma, glaucoma tubes, and failed penetrating keratoplasties.

Keywords: Corneal transplantation; DMEK; DMEK in complicated cases; hemi-DMEK; quarter-DMEK

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