Display options
Cite
Radanova M, Mihaylova G, Tasinov O, et al. New Circulating Circular RNAs with Diagnostic and Prognostic Potential in Advanced Colorectal Cancer. Int J Mol Sci. 2021;22(24)doi: 10.3390/ijms222413283.
Radanova, M., Mihaylova, G., Tasinov, O., Ivanova, D. P., Stoyanov, G. S., Nazifova-Tasinova, N., Manev, R., Salim, A., Nikolova, M., Ivanova, D. G., Conev, N., Mihaylova, Z., & Donev, I. (2021). New Circulating Circular RNAs with Diagnostic and Prognostic Potential in Advanced Colorectal Cancer. International journal of molecular sciences, 22(24), . https://doi.org/10.3390/ijms222413283
Radanova, Maria, et al. "New Circulating Circular RNAs with Diagnostic and Prognostic Potential in Advanced Colorectal Cancer." International journal of molecular sciences vol. 22,24 (2021). doi: https://doi.org/10.3390/ijms222413283
Radanova M, Mihaylova G, Tasinov O, Ivanova DP, Stoyanov GS, Nazifova-Tasinova N, Manev R, Salim A, Nikolova M, Ivanova DG, Conev N, Mihaylova Z, Donev I. New Circulating Circular RNAs with Diagnostic and Prognostic Potential in Advanced Colorectal Cancer. Int J Mol Sci. 2021 Dec 10;22(24). doi: 10.3390/ijms222413283. PMID: 34948079; PMCID: PMC8706615.
Copy Download .nbib Format: NLM
Share it on

Int J Mol Sci. 2021 Dec 10;22(24). doi: 10.3390/ijms222413283.

New Circulating Circular RNAs with Diagnostic and Prognostic Potential in Advanced Colorectal Cancer.

International journal of molecular sciences

Maria Radanova, Galya Mihaylova, Oskan Tasinov, Desislava P Ivanova, George St Stoyanov, Neshe Nazifova-Tasinova, Rostislav Manev, Ayshe Salim, Miglena Nikolova, Diana G Ivanova, Nikolay Conev, Zhasmina Mihaylova, Ivan Donev

Affiliations

  1. Department of Biochemistry, Molecular Medicine and Nutrigenomics, Medical University of Varna, 9000 Varna, Bulgaria.
  2. Clinic of General and Clinical Pathology, University Hospital "St. Marina", 9000 Varna, Bulgaria.
  3. Department of General and Clinical Pathology, Forensic Medicine and Deontology, Division of General and Clinical Pathology, Medical University of Varna, 9000 Varna, Bulgaria.
  4. Department of Oncology, Medical University of Varna, 9000 Varna, Bulgaria.
  5. Clinic of Medical Oncology, University Hospital "St. Marina", 9000 Varna, Bulgaria.
  6. Clinic of Medical Oncology, Military Medical Academy, 1000 Sofia, Bulgaria.
  7. Clinic of Medical Oncology, Hospital "Nadezhda", 1000 Sofia, Bulgaria.

PMID: 34948079 PMCID: PMC8706615 DOI: 10.3390/ijms222413283

Abstract

Circular RNAs (circRNAs) are a group of special endogenous long non-coding RNAs which are highly stable in the circulation, and, thus, more suitable as new biomarkers of colorectal cancer (CRC). The aim of our study was to explore the plasma expression levels of four circRNAs: has_circ_0001445, hsa_circ_0003028, hsa_circ_0007915 and hsa_circ_0008717 in patients with CRC and to evaluate their associations with clinicopathological characteristics and the clinical outcome of the patients. CircRNAs were extracted from patients' plasma obtained prior to chemotherapy. Their expression levels were measured by qPCR and calculated applying the 2

Keywords: circABCB10; circFUT8; circIPO11; circSMARcA5; circular RNAs; colorectal cancer

References

  1. Cell Cycle. 2017;16(22):2204-2211 - PubMed
  2. Oncotarget. 2017 Dec 21;9(15):12487-12502 - PubMed
  3. Oncol Lett. 2017 Dec;14(6):6421-6432 - PubMed
  4. Nan Fang Yi Ke Da Xue Xue Bao. 2014 Mar;34(3):354-7 - PubMed
  5. J Hepatol. 2018 Jun;68(6):1214-1227 - PubMed
  6. Onco Targets Ther. 2019 Aug 30;12:7055-7065 - PubMed
  7. Methods. 2001 Dec;25(4):402-8 - PubMed
  8. Cancers (Basel). 2021 Mar 24;13(7): - PubMed
  9. Mol Cancer. 2010 Nov 26;9:306 - PubMed
  10. Nat Commun. 2020 Sep 11;11(1):4551 - PubMed
  11. Front Oncol. 2020 Jan 31;10:48 - PubMed
  12. Cancer Sci. 2010 Oct;101(10):2087-92 - PubMed
  13. RNA Biol. 2015;12(4):381-8 - PubMed
  14. Cancers (Basel). 2021 Jun 11;13(12): - PubMed
  15. Am J Cancer Res. 2017 Jul 01;7(7):1566-1576 - PubMed
  16. Crit Rev Oncol Hematol. 2020 Jan;145:102854 - PubMed
  17. J Transl Med. 2021 Jan 6;19(1):8 - PubMed
  18. Front Pharmacol. 2020 Jan 20;10:1500 - PubMed
  19. Cell Res. 2015 Aug;25(8):981-4 - PubMed
  20. Proc Natl Acad Sci U S A. 2014 May 20;111(20):7361-6 - PubMed
  21. Int J Mol Sci. 2020 Oct 13;21(20): - PubMed
  22. Br J Cancer. 1984 Mar;49(3):375-7 - PubMed
  23. Sci Rep. 2015 Aug 07;5:12921 - PubMed
  24. Neoplasma. 2020 Sep;67(5):1063-1073 - PubMed
  25. Biochem Biophys Res Commun. 2017 Nov 25;493(3):1217-1223 - PubMed
  26. PLoS Genet. 2013;9(9):e1003777 - PubMed
  27. Aging (Albany NY). 2018 May 18;10(5):1000-1014 - PubMed
  28. Liver Int. 2006 Dec;26(10):1175-86 - PubMed
  29. Int J Mol Sci. 2020 Oct 11;21(20): - PubMed
  30. Front Oncol. 2021 Apr 29;11:632834 - PubMed
  31. Gastroenterol Res Pract. 2020 Dec 1;2020:8437250 - PubMed
  32. Front Med (Lausanne). 2021 Mar 18;8:649383 - PubMed
  33. Mol Med Rep. 2020 Mar;21(3):1217-1223 - PubMed
  34. BMC Pulm Med. 2020 Jan 13;20(1):10 - PubMed
  35. Acta Oncol. 2010;49(1):57-62 - PubMed
  36. Cancers (Basel). 2021 Jul 06;13(14): - PubMed
  37. Hepatol Res. 2010 Jan 1;40(1):83-94 - PubMed
  38. J Cell Biochem. 2019 Mar;120(3):3765-3772 - PubMed
  39. PLoS One. 2014 Apr 07;9(4):e87451 - PubMed
  40. J Cell Mol Med. 2019 May;23(5):3050-3057 - PubMed
  41. Front Genet. 2021 Feb 19;12:633750 - PubMed
  42. Dis Markers. 2019 Mar 6;2019:2473652 - PubMed
  43. PLoS One. 2015 Oct 20;10(10):e0141214 - PubMed
  44. Pharmaceuticals (Basel). 2021 Jun 27;14(7): - PubMed
  45. J Cancer Res Clin Oncol. 2016 Feb;142(2):453-63 - PubMed
  46. Cell. 2020 Apr 16;181(2):442-459.e29 - PubMed
  47. Cancers (Basel). 2020 Sep 08;12(9): - PubMed
  48. Front Oncol. 2021 Jun 23;11:601722 - PubMed
  49. Mol Ther Oncolytics. 2020 Jan 11;16:172-187 - PubMed
  50. Int J Clin Exp Pathol. 2015 Jun 01;8(6):7092-101 - PubMed
  51. Int J Mol Sci. 2018 Feb 06;19(2): - PubMed
  52. Dis Markers. 2018 Jan 23;2018:3073467 - PubMed
  53. Clin Chim Acta. 2019 May;492:37-44 - PubMed
  54. Science. 1988 Jun 3;240(4857):1285-93 - PubMed
  55. IUBMB Life. 2019 Sep;71(9):1322-1335 - PubMed
  56. Biochem Biophys Res Commun. 2020 Jun 30;527(3):638-645 - PubMed
  57. Mol Cancer. 2021 Feb 3;20(1):26 - PubMed
  58. Eur Rev Med Pharmacol Sci. 2018 Dec;22(24):8589-8598 - PubMed
  59. Bosn J Basic Med Sci. 2020 May 01;20(2):254-261 - PubMed
  60. Hum Pathol. 2010 Dec;41(12):1749-57 - PubMed

Publication Types

Grant support