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Abeln KB, Schäfers S, Ehrlich T, et al. Ross Operation With Autologous External Autograft Stabilization-Long-term Results. Ann Thorac Surg. 2021;doi: 10.1016/j.athoracsur.2021.09.017.
Abeln, K. B., Schäfers, S., Ehrlich, T., Federspiel, J. M., & Schäfers, H. J. (2021). Ross Operation With Autologous External Autograft Stabilization-Long-term Results. The Annals of thoracic surgery, . https://doi.org/10.1016/j.athoracsur.2021.09.017
Abeln, Karen B, et al. "Ross Operation With Autologous External Autograft Stabilization-Long-term Results." The Annals of thoracic surgery vol. (2021). doi: https://doi.org/10.1016/j.athoracsur.2021.09.017
Abeln KB, Schäfers S, Ehrlich T, Federspiel JM, Schäfers HJ. Ross Operation With Autologous External Autograft Stabilization-Long-term Results. Ann Thorac Surg. 2021 Oct 20; doi: 10.1016/j.athoracsur.2021.09.017. Epub 2021 Oct 20. PMID: 34678281.
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Ann Thorac Surg. 2021 Oct 20; doi: 10.1016/j.athoracsur.2021.09.017. Epub 2021 Oct 20.

Ross Operation With Autologous External Autograft Stabilization-Long-term Results.

The Annals of thoracic surgery

Karen B Abeln, Sebastian Schäfers, Tristan Ehrlich, Jan M Federspiel, Hans-Joachim Schäfers

Affiliations

  1. Department of Thoracic and Cardiovascular Surgery, Saarland University Medical Center, Homburg/Saar, Germany.
  2. Faculty of Business and Economics, University of Basel, Switzerland.
  3. Department of Thoracic and Cardiovascular Surgery, Saarland University Medical Center, Homburg/Saar, Germany. Electronic address: [email protected].

PMID: 34678281 DOI: 10.1016/j.athoracsur.2021.09.017

Abstract

BACKGROUND: We have proposed an external stabilization technique to minimize autograft dilatation after the Ross operation. This study analyzed autograft function and root dimensions after root replacement with and without external root support.

METHODS: Between October 1995 and February 2021, 185 adult patients (73% male; age, 38 ± 9 years) underwent a Ross operation as full-root replacement, 136 with support and 49 without support. Autograft function and root dimensions were determined echocardiographically. Median follow-up was 3.4 years (interquartile range, 1.13-14.74 years) and was 95% complete. Survival and freedom from reoperation were calculated. Changes in autograft root dimensions were analyzed using mixed-effect models.

RESULTS: Survival (95%) and freedom from autograft reoperation (94%) at 15 years were higher with than without support (P = .003 or P = .004). In the first 5 years, patients with support showed an indexed root size progression of 0.712 mm/(y ∙ m) (P = .003) compared with 1.554 mm/(y ∙ m) (P = .001) without. Progression rates were higher for patients without stabilization (P = .045). After 5 years, progression rates were similar in both groups at 0.248 mm/(year ∙ m) (P < .001) but with persistent a difference between the groups.

CONCLUSIONS: The Ross procedure as full-root replacement is associated with a relevant rate of autograft dilatation and reoperation. The use of external root stabilization may reduce autograft dilatation and is associated with improved survival and durability.

Copyright © 2021 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

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