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Pinto AP, Ropelle ER, Quadrilatero J, et al. Physical Exercise and Liver Autophagy: Potential Roles of IL6 and Irisin. Exerc Sport Sci Rev. 2021;doi: 10.1249/JES.0000000000000278.
Pinto, A. P., Ropelle, E. R., Quadrilatero, J., & da Silva, A. S. R. (2021). Physical Exercise and Liver Autophagy: Potential Roles of IL6 and Irisin. Exercise and sport sciences reviews, . https://doi.org/10.1249/JES.0000000000000278
Pinto, Ana P, et al. "Physical Exercise and Liver Autophagy: Potential Roles of IL6 and Irisin." Exercise and sport sciences reviews vol. (2021). doi: https://doi.org/10.1249/JES.0000000000000278
Pinto AP, Ropelle ER, Quadrilatero J, da Silva ASR. Physical Exercise and Liver Autophagy: Potential Roles of IL6 and Irisin. Exerc Sport Sci Rev. 2021 Dec 27; doi: 10.1249/JES.0000000000000278. Epub 2021 Dec 27. PMID: 34961755.
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Exerc Sport Sci Rev. 2021 Dec 27; doi: 10.1249/JES.0000000000000278. Epub 2021 Dec 27.

Physical Exercise and Liver Autophagy: Potential Roles of IL6 and Irisin.

Exercise and sport sciences reviews

Ana P Pinto, Eduardo R Ropelle, Joe Quadrilatero, Adelino S R da Silva

Affiliations

  1. Postgraduate Program in Rehabilitation and Functional Performance, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil. Laboratory of Molecular Biology of Exercise (LaBMEx), School of Applied Sciences, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil Department of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada. School of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.

PMID: 34961755 DOI: 10.1249/JES.0000000000000278

Abstract

ABSTRACT: Autophagic dysregulation contributes to liver diseases. Although some investigations have examined the effects of endurance and resistance exercise on autophagy activation, potential myokines responsible for skeletal muscle-liver crosstalk are still unknown. Based on experimental studies and bioinformatics, we hypothesized that interleukin-6 (IL6) and irisin might be key players in the contraction-induced release of molecules that regulate liver autophagic responses.

Copyright © 2021 American College of Sports Medicine.

Conflict of interest statement

The authors declare that they have no conflict of interest.

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