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Emerg Med Int. 2021 Dec 21;2021:4818312. doi: 10.1155/2021/4818312. eCollection 2021.

Experience with Tetanus in a Tertiary Care Hospital in Sudan: A Retrospective Review.

Emergency medicine international

Mumen Abdalazim Dafallah, Esraa Ahmed Ragab, Omer Ali Mohamed Ahmed Elawad

Affiliations

  1. Faculty of Medicine, University of Gezira, Wad Medani, Gezira State, Sudan.

PMID: 34970455 PMCID: PMC8714357 DOI: 10.1155/2021/4818312

Abstract

INTRODUCTION: Tetanus is still a major health issue, especially in rural areas, and is associated with high morbidity and mortality rate. This study was conducted to describe the pattern of presentation and treatment outcome among adult patients infected with tetanus in our environment.

MATERIALS AND METHODS: This is a descriptive retrospective hospital-based study conducted in Wad Medani teaching hospital, central Sudan. A total of thirty-one patients were enrolled in this study in the period between January 2018 and December 2020.

RESULTS: Thirty-one patients were infected with tetanus during the study period. They were 23 (74.2%) males and 8 (25.8%) females with a male-to-female ratio of 2.875 : 1. Their ages ranged from 20 to 70 years, and most of them (48.4%) were free workers. Acute injuries were the most common portal of entry (64.51%), and commonly involved the lower limbs (48.38%). Lock jaw (54.8%), muscle spasm (51.6%), and neck pain and stiffness (45.2%) were the most common presentation. Supportive measures along with surgical toilet and debridement, human tetanus immunoglobulin, antibiotics, and muscle relaxants were initiated in all patients. The most common antibiotics used were Penicillin V and Ceftriaxone. A muscle relaxant was administered to aid in relieving the spasms. Complication rate was 61.29% and included pulmonary and cardiovascular complications. Fifteen patients died accounting for an overall mortality rate of 48.4%.

CONCLUSIONS: Tetanus remains a disease with high morbidity and mortality. The unknown/incomplete vaccination status among study participants, inadequate management, and lack of equipped resources lead to a devastating outcome as in Sudan.

Copyright © 2021 Mumen Abdalazim Dafallah et al.

Conflict of interest statement

The authors declare that they have no conflicts of interest.

References

  1. Trop Doct. 2014 Jul;44(3):163-5 - PubMed
  2. Epidemiol Infect. 2003 Feb;130(1):71-7 - PubMed
  3. Br Med J (Clin Res Ed). 1985 Sep 7;291(6496):648-50 - PubMed
  4. Kathmandu Univ Med J (KUMJ). 2007 Jul-Sep;5(3):378-81 - PubMed
  5. Libyan J Med. 2009 Jun 01;4(2):78-80 - PubMed
  6. Trop Doct. 2005 Jul;35(3):178-81 - PubMed
  7. MMWR Morb Mortal Wkly Rep. 2002 Jul 19;51(28):613-5 - PubMed
  8. World J Emerg Surg. 2011 Jul 08;6:20 - PubMed
  9. Clin Podiatr Med Surg. 2006 Oct;23(4):769-75, vii-i - PubMed
  10. Wkly Epidemiol Rec. ;92(6):53-76 - PubMed
  11. Ann Trop Med Parasitol. 2004 Jan;98(1):59-63 - PubMed
  12. Ann Afr Med. 2009 Jul-Sep;8(3):168-72 - PubMed
  13. World J Surg. 2002 Oct;26(10):1282-5 - PubMed
  14. Afr Health Sci. 2011 Mar;11(1):36-40 - PubMed
  15. N Engl J Med. 1995 Mar 23;332(12):761-6 - PubMed
  16. J Long Term Eff Med Implants. 2003;13(3):139-54 - PubMed
  17. Niger J Clin Pract. 2007 Dec;10(4):300-3 - PubMed
  18. Infect Drug Resist. 2019 May 16;12:1289-1293 - PubMed

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