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Shuliakevich A, Muz M, Oehlmann J, et al. Assessing the genotoxic potential of freshwater sediments after extensive rain events - Lessons learned from a case study in an effluent-dominated river in Germany. Water Res. 2021;209:117921doi: 10.1016/j.watres.2021.117921.
Shuliakevich, A., Muz, M., Oehlmann, J., Nagengast, L., Schröder, K., Wolf, Y., Brückner, I., Massei, R., Brack, W., Hollert, H., & Schiwy, S. (2021). Assessing the genotoxic potential of freshwater sediments after extensive rain events - Lessons learned from a case study in an effluent-dominated river in Germany. Water research, 209117921. https://doi.org/10.1016/j.watres.2021.117921
Shuliakevich, Aliaksandra, et al. "Assessing the genotoxic potential of freshwater sediments after extensive rain events - Lessons learned from a case study in an effluent-dominated river in Germany." Water research vol. 209 (2021): 117921. doi: https://doi.org/10.1016/j.watres.2021.117921
Shuliakevich A, Muz M, Oehlmann J, Nagengast L, Schröder K, Wolf Y, Brückner I, Massei R, Brack W, Hollert H, Schiwy S. Assessing the genotoxic potential of freshwater sediments after extensive rain events - Lessons learned from a case study in an effluent-dominated river in Germany. Water Res. 2021 Dec 02;209:117921. doi: 10.1016/j.watres.2021.117921. Epub 2021 Dec 02. PMID: 34923444.
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Water Res. 2021 Dec 02;209:117921. doi: 10.1016/j.watres.2021.117921. Epub 2021 Dec 02.

Assessing the genotoxic potential of freshwater sediments after extensive rain events - Lessons learned from a case study in an effluent-dominated river in Germany.

Water research

Aliaksandra Shuliakevich, Melis Muz, Jörg Oehlmann, Laura Nagengast, Katja Schröder, Yvonne Wolf, Ira Brückner, Riccardo Massei, Werner Brack, Henner Hollert, Sabrina Schiwy

Affiliations

  1. Department Evolutionary Ecology and Environmental Toxicology, Goethe University Frankfurt/Main, Max-von-Laue-Strasse 13, 60438 Frankfurt/Main, Germany.
  2. Department of Effect-Directed Analysis, Helmholtz Centre for Environmental Research - UFZ, Permoserstrasse 15, 04318 Leipzig, Germany.
  3. Department Aquatic Ecotoxicology, Goethe University Frankfurt/Main, Max-von-Laue-Strasse 13, 60438 Frankfurt/Main, Germany.
  4. RWTH Aachen University, Institute of Biology V, Worringerweg 1, 52074 Aachen, Germany.
  5. Eifel-Rur Waterboard (WVER), Eisenbahnstr. 5, 52354 Düren, Germany.
  6. Department of Bioanalytical Ecotoxicology, Helmholtz Centre for Environmental Research - UFZ, Permoserstrasse 15, 04318 Leipzig, Germany.
  7. Department Evolutionary Ecology and Environmental Toxicology, Goethe University Frankfurt/Main, Max-von-Laue-Strasse 13, 60438 Frankfurt/Main, Germany; Department of Effect-Directed Analysis, Helmholtz Centre for Environmental Research - UFZ, Permoserstrasse 15, 04318 Leipzig, Germany.
  8. Department Evolutionary Ecology and Environmental Toxicology, Goethe University Frankfurt/Main, Max-von-Laue-Strasse 13, 60438 Frankfurt/Main, Germany. Electronic address: [email protected].

PMID: 34923444 DOI: 10.1016/j.watres.2021.117921

Abstract

Wastewater treatment plant effluents and releases from rainwater overflow basins can contribute to the input of genotoxic micropollutants in aquatic ecosystems. Predominantly lipophilic genotoxic compounds tend to sorb to particulate matter, making sediment a source and a sink of pollution. Therefore, the present study aims to investigate the genotoxic potential of freshwater sediments (i) during the dry period and (ii) after extensive rain events by collecting sediment samples in one small anthropogenically impacted river in Germany up- and downstream of the local wastewater treatment plant. The Micronucleus and Ames fluctuation assays with Salmonella typhimurium strains TA98, TA100, YG1041, and YG1042 were used to assess the genotoxic potential of organic sediment extracts. For evaluation of possible genotoxicity drivers, target analysis for 168 chemical compounds was performed. No clastogenic effects were observed, while the genotoxic potential was observed at all sampling sites primarily driven by polycyclic aromatic hydrocarbons, nitroarenes, aromatic amines, and polycyclic heteroarenes. Freshwater sediments' genotoxic potential increased after extensive rain events due to sediment perturbation and the rainwater overflow basin release. In the present study, the rainwater overflow basin was a significant source for particle-bound pollutants from untreated wastewater, suggesting its role as a possible source of genotoxic potential. The present study showed high sensitivity and applicability of the bacterial Salmonella typhimurium strains YG1041 and YG1042 to organic sediment extracts to assess the different classes of genotoxic compounds. A combination of effect-based methods and a chemical analysis was shown as a suitable tool for a genotoxic assessment of freshwater sediments.

Copyright © 2021. Published by Elsevier Ltd.

Keywords: Effluent; Genotoxicity; Rain events; Sediments

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