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Diabet Med. 2021 Dec 27;e14778. doi: 10.1111/dme.14778. Epub 2021 Dec 27.

Detecting dysglycaemia in compensated liver cirrhosis: Comparison of oral glucose tolerance test and glycated haemoglobin, with continuous glucose monitoring.

Diabetic medicine : a journal of the British Diabetic Association

Cicely V M Barron, Helen F Heenan, Harmony Thompson, Huan Chan, Jeffrey Ngu, Helen Lunt

Affiliations

  1. Department of Medicine, University of Otago Christchurch, Christchurch, New Zealand.
  2. Diabetes Outpatients, Canterbury District Health Board, Christchurch, New Zealand.
  3. Gastroenterology Department, Canterbury District Health Board, Christchurch, New Zealand.

PMID: 34957598 DOI: 10.1111/dme.14778

Abstract

AIMS: Liver cirrhosis increases the risk of developing dysglycaemia (pre-diabetes and diabetes), thus people with cirrhosis should undergo regular screening for dysglycaemia. The utility of screening using the laboratory glycated haemoglobin (HbA

METHODS: Participants ≥18 years with no known diabetes, were recruited from a gastroenterology cirrhosis surveillance register. Study measurements included a 75 g OGTT, laboratory HbA

RESULTS: All 20 participants had compensated cirrhosis. OGTT tended to diagnose more dysglycaemia (N = 7) than did HbA

CONCLUSIONS: In the setting of compensated cirrhosis, the OGTT and HbA

© 2021 Diabetes UK.

Keywords: blood glucose; glucose tolerance test; glycated haemoglobin; haptoglobins; hypoglycaemia; liver cirrhosis; monitoring, ambulatory; pre-diabetic state

References

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