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J Med Virol. 2022 Jan 02; doi: 10.1002/jmv.27543. Epub 2022 Jan 02.

Transient depletion of T cells during COVID-19 and seasonal influenza in people living with HIV.

Journal of medical virology

Eisuke Adachi, Makoto Saito, Hiroyuki Nagai, Kazuhiko Ikeuchi, Michiko Koga, Takeya Tsutsumi, Hiroshi Yotsuyanagi

Affiliations

  1. Department of Infectious Diseases and Applied Immunology, IMSUT Hospital of The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  2. Division of Infectious Diseases, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan.

PMID: 34978090 DOI: 10.1002/jmv.27543

Abstract

The cellular immune deficiency seen in people living with HIV (PLWH) is of potential concern as dysfunctional immune responses contribute to disease progression and dysregulated T cell responses can result in immunopathology. This article is protected by copyright. All rights reserved.

This article is protected by copyright. All rights reserved.

Keywords: Helper T cell; Human immunodeficiency virus; Immune responses; Influenza virus; SARS coronavirus; Virus classification

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