Display options
Cite
Minaker SW, Kofoed MC, Hieter P, et al. A nuclear proteome localization screen reveals the exquisite specificity of Gpn2 in RNA polymerase biogenesis. Cell Cycle. 2021;20(14):1361-1373doi: 10.1080/15384101.2021.1943879.
Minaker, S. W., Kofoed, M. C., Hieter, P., & Stirling, P. C. (2021). A nuclear proteome localization screen reveals the exquisite specificity of Gpn2 in RNA polymerase biogenesis. Cell cycle (Georgetown, Tex.), 20(14), 1361-1373. https://doi.org/10.1080/15384101.2021.1943879
Minaker, Sean W, et al. "A nuclear proteome localization screen reveals the exquisite specificity of Gpn2 in RNA polymerase biogenesis." Cell cycle (Georgetown, Tex.) vol. 20,14 (2021): 1361-1373. doi: https://doi.org/10.1080/15384101.2021.1943879
Minaker SW, Kofoed MC, Hieter P, Stirling PC. A nuclear proteome localization screen reveals the exquisite specificity of Gpn2 in RNA polymerase biogenesis. Cell Cycle. 2021 Jul;20(14):1361-1373. doi: 10.1080/15384101.2021.1943879. Epub 2021 Jun 28. PMID: 34180355; PMCID: PMC8344759.
Copy Download .nbib Format: NLM
Share it on

Cell Cycle. 2021 Jul;20(14):1361-1373. doi: 10.1080/15384101.2021.1943879. Epub 2021 Jun 28.

A nuclear proteome localization screen reveals the exquisite specificity of Gpn2 in RNA polymerase biogenesis.

Cell cycle (Georgetown, Tex.)

Sean W Minaker, Megan C Kofoed, Philip Hieter, Peter C Stirling

Affiliations

  1. Terry Fox Laboratories, BC Cancer Research Institute, Vancouver, Canada.
  2. Michael Smith Laboratory, University of British Columbia, Vancouver, Canada.
  3. Department of Medical Genetics, University of British Columbia, Vancouver, Canada.

PMID: 34180355 PMCID: PMC8344759 DOI: 10.1080/15384101.2021.1943879

Abstract

The GPN proteins are a conserved family of GTP-binding proteins that are involved in the assembly and subsequent import of RNA polymerase II and III. In this study, we sought to ascertain the specificity of yeast GPN2 for RNA polymerases by screening the localization of a collection of 1350 GFP-tagged nuclear proteins in WT or

Keywords: GPN2; RNA polymerase; functional genomics; protein complex biogenesis; yeast

References

  1. Nat Biotechnol. 2011 Apr;29(4):361-7 - PubMed
  2. Nature. 2003 Oct 16;425(6959):686-91 - PubMed
  3. Commun Biol. 2021 Mar 25;4(1):398 - PubMed
  4. Mol Cell. 2010 Sep 24;39(6):912-924 - PubMed
  5. Mol Cell. 2008 Apr 25;30(2):248-58 - PubMed
  6. Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):10942-10947 - PubMed
  7. Transcription. 2011 Sep-Oct;2(5):221-5 - PubMed
  8. Elife. 2017 Mar 06;6: - PubMed
  9. J Cell Biol. 2005 Jul 18;170(2):225-35 - PubMed
  10. Cell Biosci. 2012 Aug 29;2(1):30 - PubMed
  11. Mol Cell Biol. 2018 Jun 14;38(13): - PubMed
  12. J Clin Invest. 2021 Jan 4;131(1): - PubMed
  13. J Biol Chem. 1999 Jan 1;274(1):108-16 - PubMed
  14. Nucleic Acids Res. 2000 Nov 1;28(21):4212-8 - PubMed
  15. J Struct Biol. 2002 Oct-Dec;140(1-3):92-9 - PubMed
  16. Hum Mol Genet. 2017 Nov 1;26(21):4290-4300 - PubMed
  17. Mol Cell. 2011 Apr 22;42(2):261-6 - PubMed
  18. J Biol Chem. 2011 Oct 14;286(41):35553-35561 - PubMed
  19. J Struct Biol. 2002 Oct-Dec;140(1-3):79-91 - PubMed
  20. Genetics. 2013 Mar;193(3):853-64 - PubMed
  21. Methods Mol Biol. 2006;313:107-20 - PubMed
  22. Technol Cancer Res Treat. 2019 Jan 1;18:1533033819870823 - PubMed
  23. Nature. 2006 Mar 30;440(7084):637-43 - PubMed
  24. Nat Biotechnol. 2009 Apr;27(4):369-77 - PubMed
  25. Mol Cell Proteomics. 2010 Dec;9(12):2827-39 - PubMed
  26. Cancer Discov. 2012 May;2(5):401-4 - PubMed
  27. Genes Dev. 2011 May 1;25(9):972-83 - PubMed
  28. Cell Cycle. 2011 Jun 1;10(11):1828-37 - PubMed
  29. J Cell Biol. 2008 Feb 11;180(3):563-78 - PubMed
  30. PLoS Genet. 2013;9(2):e1003297 - PubMed
  31. FEBS Lett. 2017 Nov;591(21):3555-3566 - PubMed
  32. PLoS One. 2011;6(6):e20829 - PubMed
  33. EMBO Rep. 2007 Jun;8(6):569-75 - PubMed
  34. Biochim Biophys Acta Gene Regul Mech. 2017 Jul;1860(7):803-811 - PubMed
  35. Eukaryot Cell. 2008 Jun;7(6):938-48 - PubMed
  36. Mol Cell. 2009 Apr 24;34(2):168-78 - PubMed
  37. J Cell Biol. 1999 Mar 8;144(5):839-55 - PubMed
  38. Cell. 1991 May 31;65(5):785-95 - PubMed
  39. Mol Cell Biol. 2003 Mar;23(5):1656-65 - PubMed
  40. Proc Natl Acad Sci U S A. 1975 Jan;72(1):69-72 - PubMed
  41. Nature. 2020 Sep;585(7824):298-302 - PubMed
  42. Cell Cycle. 2013 Feb 1;12(3):463-72 - PubMed

Publication Types

Grant support