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Eur J Clin Microbiol Infect Dis. 2022 Jan;41(1):21-27. doi: 10.1007/s10096-021-04334-y. Epub 2021 Aug 20.

Lyme arthritis in Western Europe: a multicentre retrospective study.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology

Clémence Corre, Guillaume Coiffier, Benoit Le Goff, Marine Ferreyra, Xavier Guennic, Solène Patrat-Delon, Brigitte Degeilh, Jean-David Albert, Pierre Tattevin

Affiliations

  1. Rheumatology Department, Bretagne-Atlantique Hospital Center, Hôpital CHUBERT, Vannes, France.
  2. Reference Centre for Tick-Borne Diseases in Western France, Rennes, France.
  3. Rheumatology Department, University Hospital, Rennes, France.
  4. Rheumatology Department, GHT Rance-Emeraude, René Pléven Hospital, Dinan, France.
  5. Rheumatology Department, University Hospital, Nantes, France.
  6. Rheumatology Department, Yves Le Foll Hospital, Saint-Brieuc, France.
  7. Infectious Diseases Department, University Hospital, Rennes, France.
  8. Reference Centre for Tick-Borne Diseases in Western France, Rennes, France. [email protected].
  9. Rheumatology Department, Yves Le Foll Hospital, Saint-Brieuc, France. [email protected].
  10. Parasitology and Applied Zoology Laboratory, Rennes University Hospital, Rennes, France. [email protected].
  11. Infectious Diseases and Intensive Care Unit, Pontchaillou University Hospital, 2, rue Henri Le Guilloux, 35033 Cedex 9, Rennes, France. [email protected].

PMID: 34417687 DOI: 10.1007/s10096-021-04334-y

Abstract

To characterize Lyme arthritis, with a focus on management, and outcome. Observational retrospective multicentre study in Western France, of all consecutive cases of Lyme arthritis, documented by Borrelia burgdorferi IgG on ELISA serological testing, confirmed by Western blot, with or without positive Borrelia PCR in synovial fluid, with no alternative diagnosis. We enrolled 52 patients (29 males), with a mean age of 43 ± 19.4 years. Most patients had monoarthritis (n = 43, 82.7%), involving the knee (n = 51, 98.1%), with a median delay between symptoms onset and Lyme arthritis diagnosis of 5 months (interquartile range, 1.5-8). Synovial fluid analysis yielded median white cell count of 16,000/mm

© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Keywords: Borrelia burgdorferi; Borreliella; Lyme arthritis; Lyme borreliosis

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