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Alpaslan-Roodenberg S, Anthony D, Babiker H, et al. Ethics of DNA research on human remains: five globally applicable guidelines. Nature. 2021;599(7883):41-46doi: 10.1038/s41586-021-04008-x.
Alpaslan-Roodenberg, S., Anthony, D., Babiker, H., Bánffy, E., Booth, T., Capone, P., Deshpande-Mukherjee, A., Eisenmann, S., Fehren-Schmitz, L., Frachetti, M., Fujita, R., Frieman, C. J., Fu, Q., Gibbon, V., Haak, W., Hajdinjak, M., Hofmann, K. P., Holguin, B., Inomata, T., Kanzawa-Kiriyama, H., Keegan, W., Kelso, J., Krause, J., Kumaresan, G., Kusimba, C., Kusimba, S., Lalueza-Fox, C., Llamas, B., MacEachern, S., Mallick, S., Matsumura, H., Morales-Arce, A. Y., Matuzeviciute, G. M., Mushrif-Tripathy, V., Nakatsuka, N., Nores, R., Ogola, C., Okumura, M., Patterson, N., Pinhasi, R., Prasad, S. P. R., Prendergast, M. E., Punzo, J. L., Reich, D., Sawafuji, R., Sawchuk, E., Schiffels, S., Sedig, J., Shnaider, S., Sirak, K., Skoglund, P., Slon, V., Snow, M., Soressi, M., Spriggs, M., Stockhammer, P. W., Szécsényi-Nagy, A., Thangaraj, K., Tiesler, V., Tobler, R., Wang, C. C., Warinner, C., Yasawardene, S., & Zahir, M. (2021). Ethics of DNA research on human remains: five globally applicable guidelines. Nature, 599(7883), 41-46. https://doi.org/10.1038/s41586-021-04008-x
Alpaslan-Roodenberg, Songül, et al. "Ethics of DNA research on human remains: five globally applicable guidelines." Nature vol. 599,7883 (2021): 41-46. doi: https://doi.org/10.1038/s41586-021-04008-x
Alpaslan-Roodenberg S, Anthony D, Babiker H, Bánffy E, Booth T, Capone P, Deshpande-Mukherjee A, Eisenmann S, Fehren-Schmitz L, Frachetti M, Fujita R, Frieman CJ, Fu Q, Gibbon V, Haak W, Hajdinjak M, Hofmann KP, Holguin B, Inomata T, Kanzawa-Kiriyama H, Keegan W, Kelso J, Krause J, Kumaresan G, Kusimba C, Kusimba S, Lalueza-Fox C, Llamas B, MacEachern S, Mallick S, Matsumura H, Morales-Arce AY, Matuzeviciute GM, Mushrif-Tripathy V, Nakatsuka N, Nores R, Ogola C, Okumura M, Patterson N, Pinhasi R, Prasad SPR, Prendergast ME, Punzo JL, Reich D, Sawafuji R, Sawchuk E, Schiffels S, Sedig J, Shnaider S, Sirak K, Skoglund P, Slon V, Snow M, Soressi M, Spriggs M, Stockhammer PW, Szécsényi-Nagy A, Thangaraj K, Tiesler V, Tobler R, Wang CC, Warinner C, Yasawardene S, Zahir M. Ethics of DNA research on human remains: five globally applicable guidelines. Nature. 2021 Nov;599(7883):41-46. doi: 10.1038/s41586-021-04008-x. Epub 2021 Oct 20. PMID: 34671160.
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Nature. 2021 Nov;599(7883):41-46. doi: 10.1038/s41586-021-04008-x. Epub 2021 Oct 20.

Ethics of DNA research on human remains: five globally applicable guidelines.

Nature

Songül Alpaslan-Roodenberg, David Anthony, Hiba Babiker, Eszter Bánffy, Thomas Booth, Patricia Capone, Arati Deshpande-Mukherjee, Stefanie Eisenmann, Lars Fehren-Schmitz, Michael Frachetti, Ricardo Fujita, Catherine J Frieman, Qiaomei Fu, Victoria Gibbon, Wolfgang Haak, Mateja Hajdinjak, Kerstin P Hofmann, Brian Holguin, Takeshi Inomata, Hideaki Kanzawa-Kiriyama, William Keegan, Janet Kelso, Johannes Krause, Ganesan Kumaresan, Chapurukha Kusimba, Sibel Kusimba, Carles Lalueza-Fox, Bastien Llamas, Scott MacEachern, Swapan Mallick, Hirofumi Matsumura, Ana Y Morales-Arce, Giedre Motuzaite Matuzeviciute, Veena Mushrif-Tripathy, Nathan Nakatsuka, Rodrigo Nores, Christine Ogola, Mercedes Okumura, Nick Patterson, Ron Pinhasi, Samayamantri P R Prasad, Mary E Prendergast, Jose Luis Punzo, David Reich, Rikai Sawafuji, Elizabeth Sawchuk, Stephan Schiffels, Jakob Sedig, Svetlana Shnaider, Kendra Sirak, Pontus Skoglund, Viviane Slon, Meradeth Snow, Marie Soressi, Matthew Spriggs, Philipp W Stockhammer, Anna Szécsényi-Nagy, Kumarasamy Thangaraj, Vera Tiesler, Ray Tobler, Chuan-Chao Wang, Christina Warinner, Surangi Yasawardene, Muhammad Zahir

Affiliations

  1. Department of Genetics, Harvard Medical School, Boston, MA, USA.
  2. Department of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
  3. Department of Anthropology, Hartwick College, Oneonta, NY, USA.
  4. Department of Human Evolutionary Biology, Harvard University, Cambridge, MA, USA.
  5. Max Planck Institute for the Science of Human History, Jena, Germany.
  6. Romano-Germanic Commission of the German Archaeological Institute, Frankfurt am Main, Germany.
  7. Francis Crick Institute, London, UK.
  8. Peabody Museum of Archaeology and Ethnology, Harvard University, Cambridge, MA, USA.
  9. Department of Ancient Indian History Culture and Archaeology, Deccan College Post Graduate and Research Institute, Pune, India.
  10. Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.
  11. Department of Anthropology, University of California, Santa Cruz, CA, USA. [email protected].
  12. UCSC Genomics Institute, University of California, Santa Cruz, CA, USA. [email protected].
  13. Department of Anthropology, Washington University in St Louis, St Louis, MO, USA.
  14. Centro de Genética y Biología Molecular, Facultad de Medicina, Universidad de San Martín de Porres, Lima, Peru.
  15. School of Archaeology and Anthropology, The Australian National University, Canberra, Australian Capital Territory, Australia.
  16. Key Laboratory of Vertebrate Evolution and Human Origins, Institute of Vertebrate Paleontology and Paleoanthropology, Center for Excellence in Life and Paleoenvironment, Chinese Academy of Sciences, Beijing, China.
  17. Division of Clinical Anatomy and Biological Anthropology, Department of Human Biology, University of Cape Town, Cape Town, South Africa.
  18. Department of Anthropology, University of California, Santa Barbara, CA, USA.
  19. School of Anthropology, University of Arizona, Tucson, AZ, USA.
  20. National Museum of Nature and Science, Ibaraki, Japan.
  21. Florida Museum of Natural History, Gainesville, FL, USA.
  22. Department of Genetics, School of Biological Sciences, Madurai Kamaraj University, Madurai, India.
  23. Department of Anthropology, University of South Florida, Tampa, FL, USA.
  24. Institute of Evolutionary Biology (CSIC-UPF), Barcelona, Spain.
  25. Australian Centre for Ancient DNA, School of Biological Sciences and The Environment Institute, University of Adelaide, Adelaide, South Australia, Australia.
  26. ARC Centre of Excellence for Australian Biodiversity and Heritage, University of Adelaide, Adelaide, South Australia, Australia.
  27. Office of the Chancellors, Duke Kunshan University, Jiangsu, China.
  28. Howard Hughes Medical Institute, Boston, MA, USA.
  29. Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  30. School of Health Science, Sapporo Medical University, Sapporo, Japan.
  31. Institute of Ecology and Evolution, University of Bern, Bern, Switzerland.
  32. Lithuanian Institute of History and Department of Archaeology, History Faculty, Vilnius University, Vilnius, Lithuania.
  33. Departamento de Antropología, Facultad de Filosofía y Humanidades, Universidad Nacional de Córdoba, Instituto de Antropología de Córdoba (IDACOR), CONICET, Córdoba, Argentina.
  34. Earth Sciences Department, National Museums of Kenya, Nairobi, Kenya.
  35. Department of Genetics and Evolutionary Biology, University of São Paulo, São Paulo, Brazil.
  36. Human Evolution and Archaeological Sciences, University of Vienna, Vienna, Austria.
  37. DBT-Centre for DNA Fingerprinting and Diagnostics, Hyderabad, India.
  38. Department of Anthropology, Rice University, Houston, TX, USA. [email protected].
  39. Instituto Nacional de Antropología e Historia, Michoacán, Mexico.
  40. Department of Genetics, Harvard Medical School, Boston, MA, USA. [email protected].
  41. Department of Human Evolutionary Biology, Harvard University, Cambridge, MA, USA. [email protected].
  42. Howard Hughes Medical Institute, Boston, MA, USA. [email protected].
  43. Broad Institute of MIT and Harvard, Cambridge, MA, USA. [email protected].
  44. School of Advanced Sciences, The Graduate University for Advanced Studies (SOKENDAI), Kanagawa, Japan.
  45. Department of Anthropology, University of Alberta, Edmonton, Alberta, Canada.
  46. Department of Anthropology, Stony Brook University, Stony Brook, NY, USA.
  47. Department of Genetics, Harvard Medical School, Boston, MA, USA. [email protected].
  48. Department of Human Evolutionary Biology, Harvard University, Cambridge, MA, USA. [email protected].
  49. ArchaeoZOOlogy in Siberia and Central Asia-ZooSCAn, CNRS-IAET SB RAS International Research Laboratory, Novosibirsk, Russia.
  50. Department of Genetics, Harvard Medical School, Boston, MA, USA. [email protected].
  51. Department of Human Evolutionary Biology, Harvard University, Cambridge, MA, USA. [email protected].
  52. Department of Anatomy and Anthropology and Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
  53. The Dan David Center for Human Evolution and Biohistory Research, Tel Aviv University, Tel Aviv, Israel.
  54. Anthropology Department, University of Montana, Missoula, MO, USA.
  55. Faculty of Archaeology, Leiden University, Leiden, Netherlands.
  56. Vanuatu Cultural Centre, Port Vila, Vanuatu.
  57. Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany. [email protected].
  58. Institute for Pre- and Protohistoric Archaeology and Archaeology of the Roman Provinces, Ludwig Maximilian University, Munich, Germany. [email protected].
  59. Institute of Archaeogenomics, Research Centre for the Humanities, Eötvös Loránd Research Network, Budapest, Hungary.
  60. CSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
  61. School of Anthropological Sciences, Universidad Autónoma de Yucatán, Mérida, Mexico.
  62. Department of Anthropology and Ethnology, Institute of Anthropology, School of Sociology and Anthropology, State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, China.
  63. School of Basic Medical Sciences, Zhejiang University School of Medicine, and Institute of Asian Civilizations, Zhejiang University, Hangzhou, China.
  64. Department of Anthropology, Harvard University, Cambridge, MA, USA.
  65. Department of Anatomy, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.
  66. Department of Archaeology, Hazara University, Mansehra, Pakistan.

PMID: 34671160 DOI: 10.1038/s41586-021-04008-x

Abstract

We are a group of archaeologists, anthropologists, curators and geneticists representing diverse global communities and 31 countries. All of us met in a virtual workshop dedicated to ethics in ancient DNA research held in November 2020. There was widespread agreement that globally applicable ethical guidelines are needed, but that recent recommendations grounded in discussion about research on human remains from North America are not always generalizable worldwide. Here we propose the following globally applicable guidelines, taking into consideration diverse contexts. These hold that: (1) researchers must ensure that all regulations were followed in the places where they work and from which the human remains derived; (2) researchers must prepare a detailed plan prior to beginning any study; (3) researchers must minimize damage to human remains; (4) researchers must ensure that data are made available following publication to allow critical re-examination of scientific findings; and (5) researchers must engage with other stakeholders from the beginning of a study and ensure respect and sensitivity to stakeholder perspectives. We commit to adhering to these guidelines and expect they will promote a high ethical standard in DNA research on human remains going forward.

© 2021. The Author(s), under exclusive licence to Springer Nature Limited.

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