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Bidkhori HR, Bahrami AR, Farshchian M, et al. Mesenchymal Stem/Stromal Cells Overexpressing CXCR4. Cell Transplant. 2021;30:9636897211054498doi: 10.1177/09636897211054498.
Bidkhori, H. R., Bahrami, A. R., Farshchian, M., Heirani-Tabasi, A., Mirahmadi, M., Hasanzadeh, H., Ahmadiankia, N., Faridhosseini, R., Dastpak, M., Shabgah, A. G., & Matin, M. M. (2021). Mesenchymal Stem/Stromal Cells Overexpressing CXCR4. Cell transplantation, 309636897211054498. https://doi.org/10.1177/09636897211054498
Bidkhori, Hamid Reza, et al. "Mesenchymal Stem/Stromal Cells Overexpressing CXCR4." Cell transplantation vol. 30 (2021): 9636897211054498. doi: https://doi.org/10.1177/09636897211054498
Bidkhori HR, Bahrami AR, Farshchian M, Heirani-Tabasi A, Mirahmadi M, Hasanzadeh H, Ahmadiankia N, Faridhosseini R, Dastpak M, Shabgah AG, Matin MM. Mesenchymal Stem/Stromal Cells Overexpressing CXCR4. Cell Transplant. 2021 Jan-Dec;30:9636897211054498. doi: 10.1177/09636897211054498. PMID: 34807749; PMCID: PMC8647223.
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Cell Transplant. 2021 Jan-Dec;30:9636897211054498. doi: 10.1177/09636897211054498.

Mesenchymal Stem/Stromal Cells Overexpressing CXCR4.

Cell transplantation

Hamid Reza Bidkhori, Ahmad Reza Bahrami, Moein Farshchian, Asieh Heirani-Tabasi, Mahdi Mirahmadi, Halimeh Hasanzadeh, Naghmeh Ahmadiankia, Reza Faridhosseini, Mahtab Dastpak, Arezoo Gowhari Shabgah, Maryam M Matin

Affiliations

  1. Stem Cells and Regenerative Medicine Research Group, Academic Center for Education, Culture, and Research (ACECR)-Khorasan Razavi, Mashhad, Iran.
  2. Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.
  3. Industrial Biotechnology Research Group, Institute of Biotechnology, Ferdowsi University of Mashhad, Mashhad, Iran.
  4. Shahroud University of Medical Sciences, Shahroud, Iran.
  5. Department of Immunology, Mashhad Universityof Medical Sciences, Mashhad, Iran.
  6. School of Medicine, Bam University of Medical Sciences, Bam, Iran.
  7. Novel Diagnostics and Therapeutics Research Group, Institute of Biotechnology, Ferdowsi University of Mashhad, Mashhad, Iran.

PMID: 34807749 PMCID: PMC8647223 DOI: 10.1177/09636897211054498

Abstract

C-X-C chemokine receptor type 4 (CXCR4), initially recognized as a co-receptor for HIV, contributes to several disorders, including the WHIM (Warts, Hypogammaglobulinemia, Infections, and Myelokathexis) syndrome. CXCR4 binds to its ligand SDF-1 to make an axis involved in the homing property of stem cells. This study aimed to employ WHIM syndrome pathogenesis as an inspirational approach to reinforce cell therapies. Wild type and WHIM-type variants of the

Keywords: CXCR4R334X; WHIM syndrome; homing; lentiviral transduction; mesenchymal stem cells

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