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Jabet A, Brun S, Normand AC, et al. Extensive Dermatophytosis Caused by Terbinafine-Resistant Trichophyton indotineae, France. Emerg Infect Dis. 2022;28(1):229-233doi: 10.3201/eid2801.210883.
Jabet, A., Brun, S., Normand, A. C., Imbert, S., Akhoundi, M., Dannaoui, E., Audiffred, L., Chasset, F., Izri, A., Laroche, L., Piarroux, R., Bachmeyer, C., Hennequin, C., & Sabater, A. M. (2022). Extensive Dermatophytosis Caused by Terbinafine-Resistant Trichophyton indotineae, France. Emerging infectious diseases, 28(1), 229-233. https://doi.org/10.3201/eid2801.210883
Jabet, Arnaud, et al. "Extensive Dermatophytosis Caused by Terbinafine-Resistant Trichophyton indotineae, France." Emerging infectious diseases vol. 28,1 (2022): 229-233. doi: https://doi.org/10.3201/eid2801.210883
Jabet A, Brun S, Normand AC, Imbert S, Akhoundi M, Dannaoui E, Audiffred L, Chasset F, Izri A, Laroche L, Piarroux R, Bachmeyer C, Hennequin C, Sabater AM. Extensive Dermatophytosis Caused by Terbinafine-Resistant Trichophyton indotineae, France. Emerg Infect Dis. 2022 Jan;28(1):229-233. doi: 10.3201/eid2801.210883. PMID: 34932456; PMCID: PMC8714191.
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Emerg Infect Dis. 2022 Jan;28(1):229-233. doi: 10.3201/eid2801.210883.

Extensive Dermatophytosis Caused by Terbinafine-Resistant Trichophyton indotineae, France.

Emerging infectious diseases

Arnaud Jabet, Sophie Brun, Anne-Cecile Normand, Sebastien Imbert, Mohammad Akhoundi, Eric Dannaoui, Laeticia Audiffred, Francois Chasset, Arezki Izri, Liliane Laroche, Renaud Piarroux, Claude Bachmeyer, Christophe Hennequin, Alicia Moreno Sabater

PMID: 34932456 PMCID: PMC8714191 DOI: 10.3201/eid2801.210883

Abstract

Extensive dermatophytosis caused by terbinafine-resistant Trichophyton indotineae harboring Phe397Leu and Leu393Ser substitutions in the squalene epoxidase enzyme was diagnosed in France. Analysis of internal transcribed spacer sequences revealed the wide spread of this species in Asia and Europe. Detection of T. indotineae in animals suggests their possible role as reservoirs.

Keywords: France; Trichophyton indotineae; antimicrobial resistance; dermatophytosis; fungi; genotype VIII; ringworm; skin conditions; squalene epoxidase; terbinafine; zoonoses

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