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Pitts NB, Longbottom C, Christie A, et al. The Calcivis story - enamel caries activity assessment from technology to practice. Br Dent J. 2021;231(12):775-780doi: 10.1038/s41415-021-3755-8.
Pitts, N. B., Longbottom, C., Christie, A., Vernon, B., & Bailey, G. (2021). The Calcivis story - enamel caries activity assessment from technology to practice. British dental journal, 231(12), 775-780. https://doi.org/10.1038/s41415-021-3755-8
Pitts, Nigel B, et al. "The Calcivis story - enamel caries activity assessment from technology to practice." British dental journal vol. 231,12 (2021): 775-780. doi: https://doi.org/10.1038/s41415-021-3755-8
Pitts NB, Longbottom C, Christie A, Vernon B, Bailey G. The Calcivis story - enamel caries activity assessment from technology to practice. Br Dent J. 2021 Dec;231(12):775-780. doi: 10.1038/s41415-021-3755-8. Epub 2021 Dec 17. PMID: 34921276; PMCID: PMC8683372.
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Br Dent J. 2021 Dec;231(12):775-780. doi: 10.1038/s41415-021-3755-8. Epub 2021 Dec 17.

The Calcivis story - enamel caries activity assessment from technology to practice.

British dental journal

Nigel B Pitts, Chris Longbottom, Adam Christie, Bruce Vernon, Graham Bailey

Affiliations

  1. Faculty of Dentistry, Oral and Craniofacial Sciences, King´s College London, Tower Wing, Guy´s Hospital, London, SE1 9RT, UK. [email protected].
  2. Faculty of Dentistry, Oral and Craniofacial Sciences, King´s College London, Tower Wing, Guy´s Hospital, London, SE1 9RT, UK.
  3. Calcivis Ltd, Nine Edinburgh BioQuarter, 9 Little France Road, Edinburgh, EH16 4UX, UK.

PMID: 34921276 PMCID: PMC8683372 DOI: 10.1038/s41415-021-3755-8

Abstract

The Calcivis story is one of innovation and collaboration to deliver new technology capable of helping dentists improve patient care through solving an unmet clinical need in assessing the activity of caries lesions in enamel. Presently, there is no system routinely used in dental practice that can, in a single visit, determine whether a non-cavitated caries lesion is active or not. Calcivis has evolved since 2005, when a potential link between basic science in luminescence and differentiating initial-stage caries lesions that are actively demineralising and likely to progress, from other lesions which are inactive and currently do not need interventive care, was recognised. The 16-year journey has involved clinical academic dentists, scientists and entrepreneurs, general practitioners and their patients, together with serial investors and a core team working to patent, refine, assess and develop products to submit to regulatory approval and take to the international dental market. This journey has been made possible through effective long-term collaborations between disparate groups all sharing a common vision for the possibilities of harnessing new technology to help dental professionals provide better care for their patients.

© 2021. The Author(s), under exclusive licence to the British Dental Association.

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