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Theranostics. 2022 Jan 01;12(1):379-395. doi: 10.7150/thno.67034. eCollection 2022.

Smad3 deficiency improves islet-based therapy for diabetes and diabetic kidney injury by promoting β cell proliferation .

Theranostics

Hong-Lian Wang, Biao Wei, Hui-Jun He, Xiao-Ru Huang, Jing-Yi Sheng, Xiao-Cui Chen, Li Wang, Rui-Zhi Tan, Jian-Chun Li, Jian Liu, Si-Jin Yang, Ronald Cw Ma, Hui-Yao Lan

Affiliations

  1. Research Center for Integrated Medicine and Department of Nephrology, Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, China.
  2. Department of Medicine and Therapeutics, and Li Ka Shing Institute of Health Sciences, the Chinese University of Hong Kong, Hong Kong, 999077, China.
  3. Guangdong-Hong Kong Joint Laboratory on Immunological and Genetic Kidney Diseases, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, 510080, China.
  4. State Key Laboratory of Bioelectronics, Jiangsu Key Laboratory for Biomaterials and Devices, School of Biological Sciences & Medical Engineering, Southeast University, Nanjing, China.
  5. Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524001, China.
  6. National Traditional Chinese Medicine Clinical Research Base, Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, China.
  7. CUHK-Guangdong Provincial People's Hospital Joint Research Laboratory on Immunological and Genetic Kidney Diseases, the Chinese University of Hong Kong, Hong Kong, 999077, China.

PMID: 34987651 PMCID: PMC8690916 DOI: 10.7150/thno.67034

[No abstract available.]

© The author(s).

Keywords: E2F3; Smad3; cell cycle; diabetes; islet transplantation

Conflict of interest statement

Competing Interests: The authors have declared that no competing interest exists.

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