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SN Compr Clin Med. 2021;4(1):3. doi: 10.1007/s42399-021-01079-9. Epub 2021 Dec 27.

Comparison of Computerized Prescription Support Systems in COVID-19 Patients: INTERCheck and Drug-PIN.

SN comprehensive clinical medicine

Antonio Martocchia, Clara Bruscia, Giulia Conforti, Francesca Falangone, Valentina Marini, Alfredo Pennica, Aldo Pezzuto, Massimiliano Rocchietti March, Alberto Sentimentale, Valerio Spuntarelli, Laura Tafaro, Alberto Ricci, Maurizio Simmaco, Giorgio Sesti, Robert Preissner, Paolo Martelletti

Affiliations

  1. Sant'Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1032, 00189 Rome, Italy.
  2. Institute of Physiology and Science-IT, Charité-Universitätsmedizin Berlin, Corporate Member of Freie, Universität Berlin, Humboldt-Universität Zu Berlin, Berlin Institute of Health, Charitéplatz 1, 10117 Berlin, Germany.

PMID: 34977463 PMCID: PMC8710931 DOI: 10.1007/s42399-021-01079-9

Abstract

The coronavirus disease 19 (COVID-19) infection requires major efforts in healthcare systems, due to the high risk of mortality, particularly in subjects with significant comorbidity (≥ 2 pathologies) and polypharmacy (≥ 5 drugs). The treatment of COVID-19 needs a careful evaluation, to reduce the risk of potentially adverse drug reactions. The aim of the study was to examine the use of computerized prescription support in the management and treatment of the COVID-19 infection. We evaluated n.33 patients (51% females) admitted to the west COVID Low-Medium Intensity of Care of Sant'Andrea Hospital during the period March-April 2020 and n.42 subjects (50% females) admitted to the Internal Medicine ward (as control group), by INTERCheck® and Drug-PIN®. The comorbidity (n. pathologies), polypharmacy (n. drugs), and total INTERCheck score in COVID-19 patients and controls were, respectively (mean ± standard deviation): 5.8 ± 3.8, 7.9 ± 4.5, and 9.2 ± 7.1 and 6.8 ± 2.6, 8.0 ± 2.6, and 4.9 ± 3.8 (statistically significant for comorbidity

© The Author(s), under exclusive licence to Springer Nature Switzerland AG 2021.

Keywords: COVID-19; Comorbidity; Drug-PIN; INTERCheck; Polypharmacy

Conflict of interest statement

Conflict of InterestThe authors declare no competing interests.

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