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Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov;2021:7364-7368. doi: 10.1109/EMBC46164.2021.9630526.

An Integrated Multimodal Knee Brace Enabling Mid-Activity Tracking for Joint Health Assessment.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

Goktug C Ozmen, Brandi N Nevius, Christopher J Nichols, Samer Mabrouk, Caitlin N Teague, Omer T Inan

PMID: 34892799 DOI: 10.1109/EMBC46164.2021.9630526

Abstract

Developments in wearable technologies created opportunities for non-invasive joint health assessment while subjects perform daily activities during rehabilitation and recovery. However, existing state-of-art solutions still require a health professional or a researcher to set up the device, and most of them are not convenient for at-home use. In this paper, we demonstrate the latest version of the multimodal knee brace that our lab previously developed. This knee brace utilizes four sensing modalities: joint acoustic emissions (JAEs), electrical bioimpedance (EBI), activity and temperature. We designed custom printed-circuit boards and developed firmware to acquire high quality data. For the brace material, we used a commercial knee brace and modified it for the comfort of patients as well as to secure all electrical connections. We updated the electronics to enable rapid EBI measurements for mid-activity tracking. The performance of the multimodal knee brace was evaluated through a proof-of-concept human subjects study (n=9) with 2 days of measurement and 3 sessions per day. We obtained consistent EBI data with less than 1 Ω variance in measured impedance within six full frequency sweeps (each sweep is from 5 kHz to 100 kHz with 256 frequency steps) from each subject. Then, we asked subjects to perform 10 unloaded knee flexion/extensions, while we measured continuous 5 kHz and 100 kHz EBI at every 100 ms. The ratio of the range of reactance (ΔX

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