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Lau K, Dimitriadis PA, Mitchell C, et al. Age-related hearing loss and mild cognitive impairment: a meta-analysis and systematic review of population-based studies. J Laryngol Otol. 2021;1-16doi: 10.1017/S0022215121004114.
Lau, K., Dimitriadis, P. A., Mitchell, C., Martyn-St-James, M., Hind, D., & Ray, J. (2021). Age-related hearing loss and mild cognitive impairment: a meta-analysis and systematic review of population-based studies. The Journal of laryngology and otology, 1-16. https://doi.org/10.1017/S0022215121004114
Lau, K, et al. "Age-related hearing loss and mild cognitive impairment: a meta-analysis and systematic review of population-based studies." The Journal of laryngology and otology vol. (2021): 1-16. doi: https://doi.org/10.1017/S0022215121004114
Lau K, Dimitriadis PA, Mitchell C, Martyn-St-James M, Hind D, Ray J. Age-related hearing loss and mild cognitive impairment: a meta-analysis and systematic review of population-based studies. J Laryngol Otol. 2021 Dec 13;1-16. doi: 10.1017/S0022215121004114. Epub 2021 Dec 13. PMID: 34895373.
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J Laryngol Otol. 2021 Dec 13;1-16. doi: 10.1017/S0022215121004114. Epub 2021 Dec 13.

Age-related hearing loss and mild cognitive impairment: a meta-analysis and systematic review of population-based studies.

The Journal of laryngology and otology

K Lau, P A Dimitriadis, C Mitchell, M Martyn-St-James, D Hind, J Ray

Affiliations

  1. Department of Otolaryngology, Sheffield Teaching Hospitals, Sheffield, UK.
  2. Academic Unit of Primary Medical Care, Northern General Hospital, Sheffield, UK.
  3. Health Economics and Decisions Science, School of Health and Related Research, University of Sheffield, UK.
  4. Clinical Trials Research Unit, School of Health and Related Research, University of Sheffield, UK.

PMID: 34895373 DOI: 10.1017/S0022215121004114

Abstract

BACKGROUND: The aim of this study was to identify any relationship between hearing loss and mild cognitive impairment.

METHOD: This was a systematic review and meta-analysis of randomised controlled trials conducted using Medline and the Cochrane Library up to 24 June 2020. Prospective, cohort and cross-sectional, and observational studies that reported on the relationship between mild cognitive impairment and hearing loss were included.

RESULTS: A total of 34 studies reporting data on 48 017 participants were included. Twenty-three studies observed a significant association between hearing loss and mild cognitive impairment. The pooled risk ratio across all studies of prevalence of mild cognitive impairment in people with hearing loss was 1.44 (random-effects; 95 per cent CI = 1.27-1.64; p < 0.00001; I2 = 0 per cent). Significantly more people with mild cognitive impairment had peripheral hearing loss compared with those without (risk ratio, 1.40 random-effects; 95 per cent CI = 1.10-1.77; p = 0.005; I2 = 0 per cent). When the incidence was studied, significantly more people with peripheral hearing loss had mild cognitive impairment compared with those without (risk ratio = 2.06 random-effects; 95 per cent CI = 1.35-3.15; p = 0.0008; I2 = 97 per cent); however; a high level of statistical heterogeneity was evident.

CONCLUSION: Most of the studies included in this systematic review observed a significant association between hearing loss and mild cognitive impairment.

Keywords: Dementia; Hearing Loss; Mild Cognitive Impairment; Presbycusis

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