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Woods GA, Oikonomidis IL, Gow AG, et al. Investigation of hypomagnesaemia prevalence and underlying aetiology in a hospitalised cohort of dogs with ionised hypocalcaemia. Vet Rec. 2021;189(9):e301doi: 10.1002/vetr.301.
Woods, G. A., Oikonomidis, I. L., Gow, A. G., Tørnqvist-Johnsen, C., Boyé, P., Chng, Y., & Mellanby, R. J. (2021). Investigation of hypomagnesaemia prevalence and underlying aetiology in a hospitalised cohort of dogs with ionised hypocalcaemia. The Veterinary record, 189(9), e301. https://doi.org/10.1002/vetr.301
Woods, Glynn A, et al. "Investigation of hypomagnesaemia prevalence and underlying aetiology in a hospitalised cohort of dogs with ionised hypocalcaemia." The Veterinary record vol. 189,9 (2021): e301. doi: https://doi.org/10.1002/vetr.301
Woods GA, Oikonomidis IL, Gow AG, Tørnqvist-Johnsen C, Boyé P, Chng Y, Mellanby RJ. Investigation of hypomagnesaemia prevalence and underlying aetiology in a hospitalised cohort of dogs with ionised hypocalcaemia. Vet Rec. 2021 Nov;189(9):e301. doi: 10.1002/vetr.301. Epub 2021 Apr 19. PMID: 33870511.
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Vet Rec. 2021 Nov;189(9):e301. doi: 10.1002/vetr.301. Epub 2021 Apr 19.

Investigation of hypomagnesaemia prevalence and underlying aetiology in a hospitalised cohort of dogs with ionised hypocalcaemia.

The Veterinary record

Glynn A Woods, Ioannis L Oikonomidis, Adam G Gow, Camilla Tørnqvist-Johnsen, Pierre Boyé, Yuru Chng, Richard J Mellanby

Affiliations

  1. The Royal (Dick) School of Veterinary Studies and The Roslin Institute, Division of Veterinary Clinical Studies, The University of Edinburgh, Hospital for Small Animals, Easter Bush Veterinary Centre, Roslin, Midlothian, UK.

PMID: 33870511 DOI: 10.1002/vetr.301

Abstract

OBJECTIVES: Calcium is the most abundant mineral in the body and plays a critical role in a wide range of physiological processes. Low concentrations of ionised calcium, the most metabolically available form of calcium, have been linked to an increased risk of adverse clinical outcomes in dogs. Magnesium plays an important role in parathyroid hormone function. The objective of this study was to define the prevalence and aetiology of hypomagnesaemia in a hospitalised cohort of dogs with ionised hypocalcaemia (IHC).

METHODS: A total magnesium reference interval was established using serum biochemistry results from 346 clinically healthy dogs. The clinical records of dogs with IHC were reviewed, and concurrent serum magnesium concentrations were recorded alongside clinical signs and underlying aetiology. The prevalence, clinical presentation and aetiology of hypomagnesaemia were examined in the IHC population.

RESULTS: Two hundred and ninety-five IHC dogs were identified. Hypomagnesaemia was identified in 22%. Total magnesium concentration was significantly higher in dogs with renal disease. The most common cause of concurrent hypomagnesaemia and IHC was gastrointestinal diseases.

CONCLUSION: Low concentrations of serum magnesium occur in approximately one fifth of all dogs with IHC. Further studies are required to clarify the link between magnesium status, IHC and clinical outcome.

© 2021 British Veterinary Association.

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