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Chaves Pereira de Holanda N, de Lima Carlos I, Chaves de Holanda Limeira C, et al. Fracture Risk After Bariatric Surgery: A Systematic Literature Review and Meta-Analysis. Endocr Pract. 2021;28(1):58-69doi: 10.1016/j.eprac.2021.09.007.
Chaves Pereira de Holanda, N., de Lima Carlos, I., Chaves de Holanda Limeira, C., Cesarino de Sousa, D., Serra de Lima Junior, F. A., Telis de Vilela Araújo, A., Peres Montenegro, A. C., & Bandeira, F. (2022). Fracture Risk After Bariatric Surgery: A Systematic Literature Review and Meta-Analysis. Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 28(1), 58-69. https://doi.org/10.1016/j.eprac.2021.09.007
Chaves Pereira de Holanda, Narriane, et al. "Fracture Risk After Bariatric Surgery: A Systematic Literature Review and Meta-Analysis." Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists vol. 28,1 (2022): 58-69. doi: https://doi.org/10.1016/j.eprac.2021.09.007
Chaves Pereira de Holanda N, de Lima Carlos I, Chaves de Holanda Limeira C, Cesarino de Sousa D, Serra de Lima Junior FA, Telis de Vilela Araújo A, Peres Montenegro AC, Bandeira F. Fracture Risk After Bariatric Surgery: A Systematic Literature Review and Meta-Analysis. Endocr Pract. 2022 Jan;28(1):58-69. doi: 10.1016/j.eprac.2021.09.007. Epub 2021 Sep 23. PMID: 34563701.
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Endocr Pract. 2022 Jan;28(1):58-69. doi: 10.1016/j.eprac.2021.09.007. Epub 2021 Sep 23.

Fracture Risk After Bariatric Surgery: A Systematic Literature Review and Meta-Analysis.

Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists

Narriane Chaves Pereira de Holanda, Ingrid de Lima Carlos, Caio Chaves de Holanda Limeira, David Cesarino de Sousa, Fábio Antônio Serra de Lima Junior, André Telis de Vilela Araújo, Ana Carla Peres Montenegro, Francisco Bandeira

Affiliations

  1. Department of Endocrinology, Federal University of Paraiba, João Pessoa, Brazil; Post-Graduated Program in Health Sciences, University of Pernambuco Medical School, Recife, Brazil. Electronic address: [email protected].
  2. Department of Endocrinology, Federal University of Paraiba, João Pessoa, Brazil.
  3. Instituto de Medicina Integral de Pernambuco - IMIP, Recife, Brazil.
  4. Division of Endocrinology and Diabetes, Agamenon Magalhães Hospital, University of Pernambuco Medical School, Recife, Brazil; Post-Graduated Program in Health Sciences, University of Pernambuco Medical School, Recife, Brazil.

PMID: 34563701 DOI: 10.1016/j.eprac.2021.09.007

Abstract

OBJECTIVE: Bariatric surgery has undeniable benefits for cardiovascular and metabolic health, but it can result in negative effects on mineral and bone metabolism. This study aimed to review the current data on fractures after the main types of bariatric surgery.

METHODS: Therefore, a systematic review was performed using the electronic literature available in the databases LILACS, CENTRAL, Web of Science, Embase, and PubMed/MEDLINE, with results until January 2021. Keywords were descriptors for bariatric surgery or bariatric medicine or bariatrics or gastroplasty and bone or bones or bone fractures, referenced in all words of the text in the study.

RESULTS: The meta-analysis of observational studies and interventional trials showed that the risk of any type of fracture was higher in the surgical group than in the nonsurgical group (relative risk [RR], 1.20 [95% confidence interval {CI}, 1.15-1.26; P < .00001; Phetero < 0.000001; I

CONCLUSION: We found that bariatric procedures are associated with an increased risk of fractures, especially the malabsorptive techniques.

Copyright © 2021 AACE. Published by Elsevier Inc. All rights reserved.

Keywords: bariatric surgery; bone fractures; obesity

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