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Dusik M, Fingrova Z, Ambroz D, et al. The Role of Pulmonary Artery Wedge Pressure on the Incidence of Atrial Fibrillation and Atrial Tachycardias in Patients With Isolated Pre-capillary Pulmonary Hypertension. Physiol Res. 2021;70(6):841-849doi: 10.33549/physiolres.934706.
Dusik, M., Fingrova, Z., Ambroz, D., Jansa, P., Linhart, A., & Havranek, S. (2021). The Role of Pulmonary Artery Wedge Pressure on the Incidence of Atrial Fibrillation and Atrial Tachycardias in Patients With Isolated Pre-capillary Pulmonary Hypertension. Physiological research, 70(6), 841-849. https://doi.org/10.33549/physiolres.934706
Dusik, M, et al. "The Role of Pulmonary Artery Wedge Pressure on the Incidence of Atrial Fibrillation and Atrial Tachycardias in Patients With Isolated Pre-capillary Pulmonary Hypertension." Physiological research vol. 70,6 (2021): 841-849. doi: https://doi.org/10.33549/physiolres.934706
Dusik M, Fingrova Z, Ambroz D, Jansa P, Linhart A, Havranek S. The Role of Pulmonary Artery Wedge Pressure on the Incidence of Atrial Fibrillation and Atrial Tachycardias in Patients With Isolated Pre-capillary Pulmonary Hypertension. Physiol Res. 2021 Dec 30;70(6):841-849. doi: 10.33549/physiolres.934706. Epub 2021 Oct 30. PMID: 34717065.
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Physiol Res. 2021 Dec 30;70(6):841-849. doi: 10.33549/physiolres.934706. Epub 2021 Oct 30.

The Role of Pulmonary Artery Wedge Pressure on the Incidence of Atrial Fibrillation and Atrial Tachycardias in Patients With Isolated Pre-capillary Pulmonary Hypertension.

Physiological research

M Dusik, Z Fingrova, D Ambroz, P Jansa, A Linhart, S Havranek

Affiliations

  1. 2nd Department of Medicine, Department of Cardiovascular Medicine, General University Hospital in Prague, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic. [email protected].

PMID: 34717065 DOI: 10.33549/physiolres.934706

Abstract

Atrial fibrillation and atrial tachycardias (AF/AT) have been reported as a common condition in patients with pulmonary hypertension (PH). As yet, limited data exists about the significance of the borderline post-capillary pressure component on the occurrence of AF / AT in patients with isolated pre-capillary PH. We retrospectively studied the prevalence of AF / AT in 333 patients (mean age 61 ± 15 years, 44% males) with pre-capillary idiopathic / familiar pulmonary arterial hypertension, and inoperable chronic thromboembolic pulmonary hypertension. The prevalence of AF / AT was analyzed in different categories of pulmonary artery wedge pressure (PAWP). In the study population overall, the mean PAWP was 10.5 ± 3 mmHg, median of 11 mmHg, range 2-15 mmHg. AF / AT was diagnosed in 79 patients (24%). The proportion of AF / AT among patients with PAWP below the median (?11 mmHg) was lower than in subjects with PAWP between 12 and 15 mmHg, 30 (16%) vs. 46 (35%), p = 0.0001. Compared to the patients with PAWP?11 mmHg, subjects with PAWP between 12 and 15 mmHg were older (65 ± 13 years vs. 58 ± 16), with more prevalent arterial hyperte\nsion [100 (70%) vs. 106 (55%)] and diabetes mellitus [50 (35%) vs. 48 (25%)], showed larger size of the left atrium (42 ± 7 vs. 40 ± 6 mm), and higher values of right atrium pressure (12 ± 5 vs. 8 ± 5 mm Hg), p < 0.05 in all comparisons. The prevalence of AF / AT in the group studied increased with the growing post-capillary component.

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