Display options
Share it on

Front Psychiatry. 2021 Dec 23;12:782183. doi: 10.3389/fpsyt.2021.782183. eCollection 2021.

Affective Computing for Late-Life Mood and Cognitive Disorders.

Frontiers in psychiatry

Erin Smith, Eric A Storch, Ipsit Vahia, Stephen T C Wong, Helen Lavretsky, Jeffrey L Cummings, Harris A Eyre

Affiliations

  1. The PRODEO Institute, San Francisco, CA, United States.
  2. Organisation for Economic Co-operation and Development (OECD), Paris, France.
  3. Department of Neurology & Neurological Sciences, Stanford University, Stanford, CA, United States.
  4. Global Brain Health Institute, University of California, San Francisco, San Francisco, CA, United States.
  5. Global Brain Health Institute, Trinity College Dublin, Dublin, Ireland.
  6. Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, United States.
  7. Division of Geriatric Psychiatry, McLean Hospital, Boston, MA, United States.
  8. Division of Geriatric Psychiatry, Harvard Medical School, Boston, MA, United States.
  9. Systems Medicine and Biomedical Engineering Houston Methodist, Houston, TX, United States.
  10. Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, United States.
  11. Chambers-Grundy Center for Transformative Neuroscience, Department of Brain Health, School of Integrated Health Sciences, University of Nevada, Las Vegas (UNLV), Las Vegas, NV, United States.
  12. IMPACT, The Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, VIC, Australia.

PMID: 35002802 PMCID: PMC8732874 DOI: 10.3389/fpsyt.2021.782183

Abstract

Affective computing (also referred to as artificial emotion intelligence or emotion AI) is the study and development of systems and devices that can recognize, interpret, process, and simulate emotion or other affective phenomena. With the rapid growth in the aging population around the world, affective computing has immense potential to benefit the treatment and care of late-life mood and cognitive disorders. For late-life depression, affective computing ranging from vocal biomarkers to facial expressions to social media behavioral analysis can be used to address inadequacies of current screening and diagnostic approaches, mitigate loneliness and isolation, provide more personalized treatment approaches, and detect risk of suicide. Similarly, for Alzheimer's disease, eye movement analysis, vocal biomarkers, and driving and behavior can provide objective biomarkers for early identification and monitoring, allow more comprehensive understanding of daily life and disease fluctuations, and facilitate an understanding of behavioral and psychological symptoms such as agitation. To optimize the utility of affective computing while mitigating potential risks and ensure responsible development, ethical development of affective computing applications for late-life mood and cognitive disorders is needed.

Copyright © 2021 Smith, Storch, Vahia, Wong, Lavretsky, Cummings and Eyre.

Keywords: Alzheimer's disease; affective computing; dementia; digital phenotyping; late-life depression

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

  1. J Geriatr Psychiatry Neurol. 2019 Nov;32(6):312-318 - PubMed
  2. PLoS One. 2017 Nov 30;12(11):e0188226 - PubMed
  3. Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:3723-6 - PubMed
  4. Neurology. 1984 Jan;34(1):99-102 - PubMed
  5. Health Inf Sci Syst. 2018 Aug 27;6(1):8 - PubMed
  6. Am J Alzheimers Dis Other Demen. 2013 Mar;28(2):179-84 - PubMed
  7. J Alzheimers Dis. 2018;64(2):473-481 - PubMed
  8. Front Aging Neurosci. 2015 Jun 10;7:102 - PubMed
  9. Neuropsychiatr Dis Treat. 2007 Feb;3(1):145-52 - PubMed
  10. J Alzheimers Dis. 2015;50(3):827-38 - PubMed
  11. Behav Res Methods. 2011 Dec;43(4):903-9 - PubMed
  12. Alzheimers Dement. 2016 Apr;12(4):459-509 - PubMed
  13. IEEE Trans Nanobioscience. 2020 Jul;19(3):527-537 - PubMed
  14. Psychiatr Clin North Am. 2015 Sep;38(3):495-514 - PubMed
  15. Arch Neurol. 2010 Aug;67(8):980-6 - PubMed
  16. Gait Posture. 2010 May;32(1):113-7 - PubMed
  17. Am J Geriatr Psychiatry. 2020 Jun;28(6):591-596 - PubMed
  18. NPJ Digit Med. 2019;2: - PubMed
  19. Biomed Inform Insights. 2018 Aug 27;10:1178222618792860 - PubMed
  20. Proc SIGCHI Conf Hum Factor Comput Syst. 2016 May;2016:2098-2110 - PubMed
  21. Curr Biol. 2012 Oct 23;22(20):1975-9 - PubMed
  22. Alzheimers Dement. 2015 Jan;11(1):70-98 - PubMed
  23. Biol Psychiatry. 2012 Oct 1;72(7):580-7 - PubMed
  24. Clin Psychol Rev. 2012 Dec;32(8):704-23 - PubMed
  25. J Clin Neurosci. 2020 Aug;78:30-33 - PubMed
  26. Neuropsychiatr Dis Treat. 2014 Jul 09;10:1273-85 - PubMed
  27. J Am Geriatr Soc. 2008 Jul;56(7):1244-51 - PubMed
  28. Int J Geriatr Psychiatry. 2018 Jul;33(7):867-874 - PubMed
  29. Sensors (Basel). 2020 May 05;20(9): - PubMed
  30. J Geriatr Phys Ther. 2015 Jan-Mar;38(1):1-7 - PubMed
  31. Brain. 2013 Dec;136(Pt 12):3727-37 - PubMed
  32. Am J Geriatr Psychiatry. 2022 Jan;30(1):1-11 - PubMed
  33. J Med Internet Res. 2019 Jun 10;21(6):e12554 - PubMed
  34. J Exp Psychol Gen. 2019 Aug;148(8):1454-1462 - PubMed
  35. Am J Manag Care. 2000 Dec;6(22 Suppl):S1139-44; discussion S1145-8 - PubMed
  36. J Med Internet Res. 2019 Jul 24;21(7):e13322 - PubMed
  37. Psychogeriatrics. 2017 May;17(3):186-193 - PubMed
  38. Eur Psychiatry. 2019 Apr;57:19-25 - PubMed
  39. NPJ Digit Med. 2019 Sep 6;2:88 - PubMed
  40. PLoS One. 2015 Oct 30;10(10):e0141694 - PubMed
  41. Front Psychol. 2021 Mar 23;12:620251 - PubMed
  42. J Prev Alzheimers Dis. 2021;8(4):398-410 - PubMed
  43. Front Digit Health. 2020 Oct 08;2:567158 - PubMed
  44. Digit Biomark. 2021 Apr 16;5(1):78-88 - PubMed
  45. IEEE Trans Affect Comput. 2013 Apr-Jun;4(2):142-150 - PubMed
  46. Am J Alzheimers Dis Other Demen. 2009 Jun-Jul;24(3):258-66 - PubMed
  47. Geriatr Gerontol Int. 2015 Jul;15(7):817-26 - PubMed
  48. Soc Neurosci. 2021 Feb;16(1):26-38 - PubMed
  49. Clin Physiol Funct Imaging. 2010 Jan;30(1):51-6 - PubMed
  50. Neuron. 2014 Nov 5;84(3):608-22 - PubMed
  51. Neuroepidemiology. 2013;41(3-4):139-45 - PubMed
  52. Dement Geriatr Cogn Disord. 2003;15(3):132-42 - PubMed
  53. J Am Med Inform Assoc. 2020 Jul 1;27(7):1007-1018 - PubMed
  54. Alzheimers Res Ther. 2021 Jun 14;13(1):115 - PubMed
  55. Lancet Neurol. 2014 Aug;13(8):788-94 - PubMed
  56. Proc ACM Int Conf Multimodal Interact. 2014 Nov;2014:112-119 - PubMed
  57. Sci Rep. 2019 Sep 16;9(1):13414 - PubMed
  58. J Clin Psychiatry. 2011 Feb;72(2):126-33 - PubMed
  59. PLoS One. 2019 May 22;14(5):e0216591 - PubMed
  60. Am J Alzheimers Dis Other Demen. 2012 Mar;27(2):100-6 - PubMed
  61. Percept Mot Skills. 2014 Aug;119(1):259-78 - PubMed
  62. J Gerontol Nurs. 2017 Dec 1;43(12):35-43 - PubMed
  63. J Alzheimers Dis. 2015;50(3):687-98 - PubMed
  64. Brain. 2005 Jun;128(Pt 6):1267-76 - PubMed
  65. Geroscience. 2021 Feb;43(1):297-308 - PubMed
  66. Biol Psychiatry. 1998 Apr 15;43(8):584-94 - PubMed
  67. Proc ACM Int Conf Multimodal Interact. 2015 Nov;2015:307-310 - PubMed
  68. Am J Geriatr Psychiatry. 2021 Jul;29(7):698-703 - PubMed
  69. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2006 Sep-Dec;13(3-4):636-51 - PubMed
  70. Alzheimers Dement (Amst). 2015 Mar 29;1(1):112-24 - PubMed
  71. Front Pharmacol. 2020 Feb 04;10:1699 - PubMed
  72. IEEE J Biomed Health Inform. 2018 Mar;22(2):525-536 - PubMed
  73. J Nurs Scholarsh. 2018 Nov;50(6):612-622 - PubMed
  74. Int J Psychophysiol. 2014 Jul;93(1):12-6 - PubMed
  75. Alzheimers Res Ther. 2021 Jun 4;13(1):109 - PubMed
  76. Biomark Med. 2016 Jul;10(7):677-80 - PubMed
  77. Age Ageing. 2014 Nov;43(6):741-3 - PubMed
  78. JMIR Mhealth Uhealth. 2019 Jul 24;7(7):e13209 - PubMed

Publication Types