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Konno M, Osawa T, Hotta K, et al. Primary renal leiomyosarcoma with a tumor thrombus in the inferior vena cava. IJU Case Rep. 2021;5(1):66-69doi: 10.1002/iju5.12396.
Konno, M., Osawa, T., Hotta, K., Shimizu, A., Abe, T., Matsumoto, R., Kikuchi, H., & Shinohara, N. (2022). Primary renal leiomyosarcoma with a tumor thrombus in the inferior vena cava. IJU case reports, 5(1), 66-69. https://doi.org/10.1002/iju5.12396
Konno, Mikio, et al. "Primary renal leiomyosarcoma with a tumor thrombus in the inferior vena cava." IJU case reports vol. 5,1 (2022): 66-69. doi: https://doi.org/10.1002/iju5.12396
Konno M, Osawa T, Hotta K, Shimizu A, Abe T, Matsumoto R, Kikuchi H, Shinohara N. Primary renal leiomyosarcoma with a tumor thrombus in the inferior vena cava. IJU Case Rep. 2021 Nov 19;5(1):66-69. doi: 10.1002/iju5.12396. eCollection 2022 Jan. PMID: 35005478; PMCID: PMC8720715.
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IJU Case Rep. 2021 Nov 19;5(1):66-69. doi: 10.1002/iju5.12396. eCollection 2022 Jan.

Primary renal leiomyosarcoma with a tumor thrombus in the inferior vena cava.

IJU case reports

Mikio Konno, Takahiro Osawa, Kiyohiko Hotta, Ai Shimizu, Takashige Abe, Ryuji Matsumoto, Hiroshi Kikuchi, Nobuo Shinohara

Affiliations

  1. Department of Urology Hokkaido University Hospital Sapporo Japan.
  2. Department of Surgical Pathology Hokkaido University Hospital Sapporo Japan.

PMID: 35005478 PMCID: PMC8720715 DOI: 10.1002/iju5.12396

Abstract

INTRODUCTION: We report a rare case of primary renal leiomyosarcoma with a tumor thrombus in the inferior vena cava.

CASE PRESENTATION: A 54-year-old woman presented with right flank pain and abdominal distension. Physical examination findings were unremarkable. Abdominal computed tomography revealed a heterogeneously enhancing right solid renal mass with a thrombus in the renal vein extending into the inferior vena cava. Magnetic resonance imaging demonstrated a renal tumor with a thrombus about 4 cm below the hepatic vein. Chest computed tomography and bone scintigraphy were negative. The patient underwent right radical nephrectomy and vena cava thrombectomy. Histophathologic evaluation of the resected tumor confirmed the diagnosis of leiomyosarcoma. She underwent no adjuvant therapy. Seven months after surgery, the patient died following a 2-month history of multiple pulmonary and hepatic metastases.

CONCLUSION: This report highlights the importance of considering the possibility of renal leiomyosarcoma invasion to the inferior vena cava, similar to renal cell carcinoma.

© 2021 The Authors. IJU Case Reports published by John Wiley & Sons Australia, Ltd on behalf of Japanese Urological Association.

Keywords: kidney; leiomyosarcoma; thrombus; vena cava

Conflict of interest statement

The authors declare no conflict of interest.

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