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Nunes JPS, Andrieux P, Brochet P, et al. Co-Exposure of Cardiomyocytes to IFN-γ and TNF-α Induces Mitochondrial Dysfunction and Nitro-Oxidative Stress: Implications for the Pathogenesis of Chronic Chagas Disease Cardiomyopathy. Front Immunol. 2021;12:755862doi: 10.3389/fimmu.2021.755862.
Nunes, J. P. S., Andrieux, P., Brochet, P., Almeida, R. R., Kitano, E., Honda, A. K., Iwai, L. K., Andrade-Silva, D., Goudenège, D., Alcântara Silva, K. D., Vieira, R. S., Levy, D., Bydlowski, S. P., Gallardo, F., Torres, M., Bocchi, E. A., Mano, M., Santos, R. H. B., Bacal, F., Pomerantzeff, P., Laurindo, F. R. M., Teixeira, P. C., Nakaya, H. I., Kalil, J., Procaccio, V., Chevillard, C., & Cunha-Neto, E. (2021). Co-Exposure of Cardiomyocytes to IFN-γ and TNF-α Induces Mitochondrial Dysfunction and Nitro-Oxidative Stress: Implications for the Pathogenesis of Chronic Chagas Disease Cardiomyopathy. Frontiers in immunology, 12755862. https://doi.org/10.3389/fimmu.2021.755862
Nunes, João Paulo Silva, et al. "Co-Exposure of Cardiomyocytes to IFN-γ and TNF-α Induces Mitochondrial Dysfunction and Nitro-Oxidative Stress: Implications for the Pathogenesis of Chronic Chagas Disease Cardiomyopathy." Frontiers in immunology vol. 12 (2021): 755862. doi: https://doi.org/10.3389/fimmu.2021.755862
Nunes JPS, Andrieux P, Brochet P, Almeida RR, Kitano E, Honda AK, Iwai LK, Andrade-Silva D, Goudenège D, Alcântara Silva KD, Vieira RS, Levy D, Bydlowski SP, Gallardo F, Torres M, Bocchi EA, Mano M, Santos RHB, Bacal F, Pomerantzeff P, Laurindo FRM, Teixeira PC, Nakaya HI, Kalil J, Procaccio V, Chevillard C, Cunha-Neto E. Co-Exposure of Cardiomyocytes to IFN-γ and TNF-α Induces Mitochondrial Dysfunction and Nitro-Oxidative Stress: Implications for the Pathogenesis of Chronic Chagas Disease Cardiomyopathy. Front Immunol. 2021 Nov 11;12:755862. doi: 10.3389/fimmu.2021.755862. eCollection 2021. PMID: 34867992; PMCID: PMC8632642.
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Front Immunol. 2021 Nov 11;12:755862. doi: 10.3389/fimmu.2021.755862. eCollection 2021.

Co-Exposure of Cardiomyocytes to IFN-γ and TNF-α Induces Mitochondrial Dysfunction and Nitro-Oxidative Stress: Implications for the Pathogenesis of Chronic Chagas Disease Cardiomyopathy.

Frontiers in immunology

João Paulo Silva Nunes, Pauline Andrieux, Pauline Brochet, Rafael Ribeiro Almeida, Eduardo Kitano, André Kenji Honda, Leo Kei Iwai, Débora Andrade-Silva, David Goudenège, Karla Deysiree Alcântara Silva, Raquel de Souza Vieira, Débora Levy, Sergio Paulo Bydlowski, Frédéric Gallardo, Magali Torres, Edimar Alcides Bocchi, Miguel Mano, Ronaldo Honorato Barros Santos, Fernando Bacal, Pablo Pomerantzeff, Francisco Rafael Martins Laurindo, Priscila Camillo Teixeira, Helder I Nakaya, Jorge Kalil, Vincent Procaccio, Christophe Chevillard, Edecio Cunha-Neto

Affiliations

  1. Laboratory of Immunology, Heart Institute (Incor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
  2. Division of Clinical Immunology and Allergy, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
  3. iii-Institute for Investigation in Immunology, Instituto Nacional de Ciência e Tecnologia (INCT), São Paulo, Brazil.
  4. INSERM, UMR_1090, Aix Marseille Université, TAGC Theories and Approaches of Genomic Complexity, Institut MarMaRa, Marseille, France.
  5. Laboratório Especial de Toxinologia Aplicada, Center of Toxins, Immune-Response and Cell Signaling (CeTICS), Instituto Butantan, São Paulo, Brazil.
  6. Department of Biochemistry and Genetics, University Hospital of Angers, Angers, France.
  7. Heart Failure Team, Heart Institute (Incor) Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
  8. Functional Genomics and RNA-based Therapeutics Laboratory, Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal.
  9. Division of Surgery, Heart Institute, School of Medicine, University of São Paulo, São Paulo, Brazil.
  10. Laboratory of Vascular Biology, Heart Institute of the School of Medicine, University of São Paulo, São Paulo, Brazil.
  11. Translational Research Sciences, Pharma Research and Early Development F. Hoffmann-La Roche, Basel, Switzerland.
  12. Hospital Israelita Albert Einstein, São Paulo, Brazil.
  13. MitoLab, UMR CNRS 6015-INSERM U1083, Université d'Angers, Angers, France.

PMID: 34867992 PMCID: PMC8632642 DOI: 10.3389/fimmu.2021.755862

Abstract

Infection by the protozoan

Copyright © 2021 Nunes, Andrieux, Brochet, Almeida, Kitano, Honda, Iwai, Andrade-Silva, Goudenège, Alcântara Silva, Vieira, Levy, Bydlowski, Gallardo, Torres, Bocchi, Mano, Santos, Bacal, Pomerantzeff, Laurindo, Teixeira, Nakaya, Kalil, Procaccio, Chevillard and Cunha-Neto.

Keywords: chronic Chagas disease cardiomyopathy; energy metabolism; interferon gamma; mitochondria ; mitochondrial dysfunction

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

  1. J Am Coll Cardiol. 2017 Sep 19;70(12):1510-1524 - PubMed
  2. Clin Immunol Immunopathol. 1997 May;83(2):165-72 - PubMed
  3. Circ Res. 1999 Aug 20;85(4):357-63 - PubMed
  4. Nat Protoc. 2007;2(8):1896-906 - PubMed
  5. EBioMedicine. 2018 Apr;30:303-316 - PubMed
  6. J Mol Med (Berl). 2011 Jul;89(7):667-76 - PubMed
  7. Pharmacol Rev. 2018 Apr;70(2):348-383 - PubMed
  8. Braz J Med Biol Res. 1998 Jan;31(1):133-7 - PubMed
  9. Oxid Med Cell Longev. 2020 Mar 26;2020:9081813 - PubMed
  10. Card Fail Rev. 2017 Apr;3(1):7-11 - PubMed
  11. J Neurochem. 2015 Feb;132(4):443-51 - PubMed
  12. Redox Biol. 2018 Jun;16:146-156 - PubMed
  13. Heart Fail Rev. 2014 Mar;19(2):227-36 - PubMed
  14. Mol Cell Biol. 1997 Nov;17(11):6746-54 - PubMed
  15. Bioinformatics. 2014 Apr 1;30(7):923-30 - PubMed
  16. Mol Cell Biol. 2000 Aug;20(15):5680-9 - PubMed
  17. Nat Rev Cardiol. 2017 Apr;14(4):238-250 - PubMed
  18. Front Immunol. 2018 Dec 03;9:2791 - PubMed
  19. Free Radic Biol Med. 2009 Nov 15;47(10):1414-21 - PubMed
  20. Biochim Biophys Acta. 2014 Nov;1843(11):2645-61 - PubMed
  21. Bioinformatics. 2014 Aug 1;30(15):2114-20 - PubMed
  22. Genome Biol. 2014;15(12):550 - PubMed
  23. Minerva Cardioangiol. 2010 Apr;58(2):213-29 - PubMed
  24. Bioinformatics. 2016 Jan 15;32(2):292-4 - PubMed
  25. Front Immunol. 2020 Jul 07;11:1386 - PubMed
  26. Biosci Rep. 2019 Jan 3;39(1): - PubMed
  27. PLoS Negl Trop Dis. 2011 Jun;5(6):e1205 - PubMed
  28. J Clin Immunol. 2021 Jul;41(5):1048-1063 - PubMed
  29. Front Cell Dev Biol. 2021 Feb 22;9:625020 - PubMed
  30. Redox Biol. 2019 Feb;21:101059 - PubMed
  31. Mediators Inflamm. 2014;2014:683230 - PubMed
  32. J Mol Biol. 2007 Jun 15;369(4):967-84 - PubMed
  33. Curr Protoc Mouse Biol. 2017 Mar 2;7(1):47-54 - PubMed
  34. Clin Dev Immunol. 2012;2012:361730 - PubMed
  35. J Biol Chem. 2011 Apr 8;286(14):12245-56 - PubMed
  36. Cardiovasc Res. 2014 Jul 1;103(1):90-9 - PubMed
  37. Cardiovasc Toxicol. 2003;3(3):229-54 - PubMed
  38. Front Cardiovasc Med. 2018 Jun 06;5:68 - PubMed
  39. Nat Biotechnol. 2008 Dec;26(12):1367-72 - PubMed
  40. Mediators Inflamm. 2014;2014:914326 - PubMed
  41. Molecules. 2020 Nov 23;25(22): - PubMed
  42. Circ Res. 2012 Apr 13;110(8):1125-38 - PubMed
  43. Sci Rep. 2015 Oct 20;5:15434 - PubMed
  44. J Mol Cell Cardiol. 2005 Jul;39(1):133-47 - PubMed
  45. PLoS Negl Trop Dis. 2020 Dec 22;14(12):e0008889 - PubMed
  46. J Immunol. 2008 Oct 1;181(7):4461-70 - PubMed
  47. Infect Immun. 1998 Mar;66(3):1208-15 - PubMed
  48. ESC Heart Fail. 2021 Apr;8(2):1460-1471 - PubMed
  49. Autoimmun Rev. 2011 Jan;10(3):163-5 - PubMed
  50. J Am Heart Assoc. 2012 Dec;1(6):e003855 - PubMed
  51. Am J Trop Med Hyg. 1993 May;48(5):637-44 - PubMed
  52. Circ Res. 2013 Aug 16;113(5):603-16 - PubMed
  53. Diabetes Metab Res Rev. 2014 Nov;30(8):669-78 - PubMed
  54. Biochem J. 2004 Aug 1;381(Pt 3):743-52 - PubMed
  55. Arq Bras Cardiol. 2010 Aug;95(2):264-70 - PubMed
  56. J Proteome Res. 2008 Feb;7(2):731-40 - PubMed
  57. Bioinformatics. 2013 Jan 1;29(1):15-21 - PubMed
  58. Biochem J. 2018 Apr 5;475(7):1235-1251 - PubMed
  59. PLoS Pathog. 2016 Oct 20;12(10):e1005954 - PubMed
  60. Infect Immun. 2016 Nov 18;84(12):3527-3541 - PubMed
  61. Am J Nephrol. 2007;27(6):649-60 - PubMed
  62. J Cell Physiol. 2019 Nov;234(11):20453-20468 - PubMed
  63. J Pathol. 2019 Mar;247(3):320-332 - PubMed
  64. Mol Cell Proteomics. 2014 Sep;13(9):2513-26 - PubMed
  65. Chin Med J (Engl). 2015 Dec 5;128(23):3211-8 - PubMed
  66. J Cardiovasc Transl Res. 2010 Aug;3(4):314-20 - PubMed
  67. PLoS Negl Trop Dis. 2012;6(10):e1867 - PubMed
  68. Cardiovasc Res. 2001 Mar;49(4):798-807 - PubMed
  69. Free Radic Biol Med. 2014 Oct;75 Suppl 1:S32 - PubMed
  70. Arterioscler Thromb Vasc Biol. 2020 Jul;40(7):1722-1737 - PubMed
  71. Cell Signal. 2013 Oct;25(10):1939-48 - PubMed
  72. J Autoimmun. 2001 Aug;17(1):99-107 - PubMed
  73. Microbes Infect. 2008 Aug-Sep;10(10-11):1201-9 - PubMed
  74. Adv Parasitol. 2011;76:153-70 - PubMed
  75. J Biol Chem. 2010 Apr 9;285(15):11596-606 - PubMed
  76. Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2420-E2429 - PubMed
  77. Lab Invest. 2007 Apr;87(4):326-35 - PubMed
  78. Cells. 2019 Apr 25;8(4): - PubMed
  79. Clin Infect Dis. 2017 Oct 1;65(7):1103-1111 - PubMed
  80. Infect Immun. 1995 Dec;63(12):4862-7 - PubMed
  81. Acta Neuropathol. 2017 Oct;134(4):655-666 - PubMed

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