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Joyce P, Dening TJ, Meola TR, et al. Contrasting Anti-obesity Effects of Smectite Clays and Mesoporous Silica in Sprague-Dawley Rats. ACS Appl Bio Mater. 2020;3(11):7779-7788doi: 10.1021/acsabm.0c00969.
Joyce, P., Dening, T. J., Meola, T. R., Wignall, A., Ulmefors, H., Kovalainen, M., & Prestidge, C. A. (2020). Contrasting Anti-obesity Effects of Smectite Clays and Mesoporous Silica in Sprague-Dawley Rats. ACS applied bio materials, 3(11), 7779-7788. https://doi.org/10.1021/acsabm.0c00969
Joyce, Paul, et al. "Contrasting Anti-obesity Effects of Smectite Clays and Mesoporous Silica in Sprague-Dawley Rats." ACS applied bio materials vol. 3,11 (2020): 7779-7788. doi: https://doi.org/10.1021/acsabm.0c00969
Joyce P, Dening TJ, Meola TR, Wignall A, Ulmefors H, Kovalainen M, Prestidge CA. Contrasting Anti-obesity Effects of Smectite Clays and Mesoporous Silica in Sprague-Dawley Rats. ACS Appl Bio Mater. 2020 Nov 16;3(11):7779-7788. doi: 10.1021/acsabm.0c00969. Epub 2020 Nov 05. PMID: 35019518.
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ACS Appl Bio Mater. 2020 Nov 16;3(11):7779-7788. doi: 10.1021/acsabm.0c00969. Epub 2020 Nov 05.

Contrasting Anti-obesity Effects of Smectite Clays and Mesoporous Silica in Sprague-Dawley Rats.

ACS applied bio materials

Paul Joyce, Tahnee J Dening, Tahlia R Meola, Anthony Wignall, Hanna Ulmefors, Miia Kovalainen, Clive A Prestidge

Affiliations

  1. UniSA Clinical & Health Sciences, University of South Australia, Adelaide 5000, South Australia, Australia.
  2. ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, University of South Australia, Adelaide 5000, South Australia, Australia.
  3. Research Unit of Biomedicine and Biocenter of Oulu, Faculty of Medicine, University of Oulu, P.O. Box 5000, Oulu FI-90014, Finland.

PMID: 35019518 DOI: 10.1021/acsabm.0c00969

Abstract

Porous colloids have been shown to exert unique bioactivities for mediating lipid (fat) metabolism and thereby offer significant potential as anti-obesity therapies. In this study, we compare the capacity for two classes of colloids, that is, smectite clays (Laponite XLG, LAP; montmorillonite, MMT) and mesoporous silica (SBA-15 ordered silica; MPS), to impede intestinal lipid hydrolysis and provoke lipid and carbohydrate excretion through adsorption within their particle matrices. A two-stage

Keywords: anti-obesity; fat digestion; functional foods; lipolysis; obesity

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