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Cushman DM, Knox J, Kobayashi JK, et al. Does anesthetic relief correspond to future pain relief? A prospective trial examining future pain relief for ultrasound-guided corticosteroid-anesthetic injections. Am J Phys Med Rehabil. 2022;doi: 10.1097/PHM.0000000000001959.
Cushman, D. M., Knox, J., Kobayashi, J. K., Zarate, M., Wheelwright, J. C., Monson, N., English, J., & Teramoto, M. (2022). Does anesthetic relief correspond to future pain relief? A prospective trial examining future pain relief for ultrasound-guided corticosteroid-anesthetic injections. American journal of physical medicine & rehabilitation, . https://doi.org/10.1097/PHM.0000000000001959
Cushman, Daniel M, et al. "Does anesthetic relief correspond to future pain relief? A prospective trial examining future pain relief for ultrasound-guided corticosteroid-anesthetic injections." American journal of physical medicine & rehabilitation vol. (2022). doi: https://doi.org/10.1097/PHM.0000000000001959
Cushman DM, Knox J, Kobayashi JK, Zarate M, Wheelwright JC, Monson N, English J, Teramoto M. Does anesthetic relief correspond to future pain relief? A prospective trial examining future pain relief for ultrasound-guided corticosteroid-anesthetic injections. Am J Phys Med Rehabil. 2022 Jan 10; doi: 10.1097/PHM.0000000000001959. Epub 2022 Jan 10. PMID: 35019871.
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Am J Phys Med Rehabil. 2022 Jan 10; doi: 10.1097/PHM.0000000000001959. Epub 2022 Jan 10.

Does anesthetic relief correspond to future pain relief? A prospective trial examining future pain relief for ultrasound-guided corticosteroid-anesthetic injections.

American journal of physical medicine & rehabilitation

Daniel M Cushman, Jordan Knox, Jacqueline K Kobayashi, Marisol Zarate, John C Wheelwright, Nicholas Monson, Joy English, Masaru Teramoto

Affiliations

  1. University of Utah Division of Physical Medicine & Rehabilitation, Salt Lake City, UT 84108 University of Utah Department of Family & Preventive Medicine, Salt Lake City, UT 84108 University of Utah School of Medicine, Salt Lake City, UT 84108 University of Utah Department of Orthopaedics, Salt Lake City, UT 84108.

PMID: 35019871 DOI: 10.1097/PHM.0000000000001959

Abstract

OBJECTIVE: To prospectively evaluate the association between immediate pain relief from injections of local anesthetic with corticosteroid and subsequent pain relief up to three months. The secondary aim was to examine the time until subjective pain relief following these injections.

DESIGN: This was a single-center, prospective study of patients undergoing ultrasound-guided corticosteroid injections for musculoskeletal pain. Subjects completed follow-up surveys at two weeks (2w), one month (1 m), and three months (3 m) post-injections. χ2 tests and sensitivity analysis were used to examine the primary outcome, at least 50% relief from the injection. Regression modeling examined the effects of demographic and injection-related variables on outcome measures.

RESULTS: A total of 132 patients were enrolled (55% female, mean age 52 years). Response rates were 87.1% at 2w and 77.2% at 3 m. The positive likelihood ratios from 50% initial pain relief ranged from 1.22 to 1.29 at the three time points, while the negative likelihood ratios ranged from 0.54 to 0.63. More than 75% of participants reported subjective pain relief by day four post-injection.

CONCLUSION: The predictive value of immediate pain relief for subsequent longer-term pain relief from corticosteroid-anesthetic injections is not particularly high. Most patients will obtain pain relief within four days of a corticosteroid injection.

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