Display options
Cite
Yalçin F, Yalçin H, Küçükler N, et al. Basal Septal Hypertrophy as the Early Imaging Biomarker for Adaptive Phase of Remodeling Prior to Heart Failure. J Clin Med. 2021;11(1)doi: 10.3390/jcm11010075.
Yalçin, F., Yalçin, H., Küçükler, N., Arslan, S., Akkuş, O., Kurtul, A., & Abraham, M. R. (2021). Basal Septal Hypertrophy as the Early Imaging Biomarker for Adaptive Phase of Remodeling Prior to Heart Failure. Journal of clinical medicine, 11(1), . https://doi.org/10.3390/jcm11010075
Yalçin, Fatih, et al. "Basal Septal Hypertrophy as the Early Imaging Biomarker for Adaptive Phase of Remodeling Prior to Heart Failure." Journal of clinical medicine vol. 11,1 (2021). doi: https://doi.org/10.3390/jcm11010075
Yalçin F, Yalçin H, Küçükler N, Arslan S, Akkuş O, Kurtul A, Abraham MR. Basal Septal Hypertrophy as the Early Imaging Biomarker for Adaptive Phase of Remodeling Prior to Heart Failure. J Clin Med. 2021 Dec 24;11(1). doi: 10.3390/jcm11010075. PMID: 35011816; PMCID: PMC8745483.
Copy Download .nbib Format: NLM
Share it on

J Clin Med. 2021 Dec 24;11(1). doi: 10.3390/jcm11010075.

Basal Septal Hypertrophy as the Early Imaging Biomarker for Adaptive Phase of Remodeling Prior to Heart Failure.

Journal of clinical medicine

Fatih Yalçin, Hulya Yalçin, Nagehan Küçükler, Serbay Arslan, Oguz Akkuş, Alparslan Kurtul, Maria Roselle Abraham

Affiliations

  1. Cardiology UCSF Health, Department of Medicine, University of California at San Francisco, San Francisco, CA 94143, USA.
  2. Department of Cardiology, Mustafa Kemal University, Antakya 31100, Turkey.

PMID: 35011816 PMCID: PMC8745483 DOI: 10.3390/jcm11010075

Abstract

Hypertension plays a dominant role in the development of left ventricular (LV) remodeling and heart failure, in addition to being the main risk factor for coronary artery disease. In this review, we focus on the focal geometric and functional tissue aspects of the LV septal base, since basal septal hypertrophy (BSH), as the early imaging biomarker of LV remodeling due to hypertensive heart disease, is detected in cross-sectional clinic studies. In addition, the validation of BSH by animal studies using third generation microimaging and relevant clinical observations are also discussed in the report. Finally, an evaluation of both human and animal quantitative imaging studies and the importance of combined cardiac imaging methods and stress-induction in the separation of adaptive and maladaptive phases of the LV remodeling are pointed out. As a result, BSH, as the early imaging biomarker and quantitative follow-up of functional analysis in hypertension, could possibly contribute to early treatment in a timely fashion in the prevention of hypertensive disease progression to heart failure. A variety of stress stimuli in etiopathogenesis and the difficulty of diagnosing pure hemodynamic overload mediated BSH lead to an absence of the certain prevalence of this particular finding in the population.

Keywords: basal septal hypertrophy; early imaging biomarker; heart failure; hypertension and stressed heart morphology

References

  1. Int J Cardiol. 1982;2(1):103-8 - PubMed
  2. N Engl J Med. 1990 May 31;322(22):1561-6 - PubMed
  3. Hypertension. 2002 Jan;39(1):75-80 - PubMed
  4. J Am Pharm Assoc (2003). 2008 Jan-Feb;48(1):23-31 - PubMed
  5. Hypertension. 1985 Nov-Dec;7(6 Pt 1):979-88 - PubMed
  6. J Card Fail. 2005 Apr;11(3):177-87 - PubMed
  7. Am J Physiol Heart Circ Physiol. 2005 Jul;289(1):H8-H16 - PubMed
  8. JAMA. 2006 Nov 8;296(18):2209-16 - PubMed
  9. Blood Press Monit. 2020 Apr;25(2):118-119 - PubMed
  10. Circ Heart Fail. 2010 May;3(3):420-30 - PubMed
  11. Am J Cardiol. 1994 Feb 1;73(4):247-52 - PubMed
  12. Blood Press Monit. 2019 Jun;24(3):110-113 - PubMed
  13. Int J Cardiol. 2009 Jun 26;135(2):251-2 - PubMed
  14. J Hypertens. 2010 Jul;28(7):1541-6 - PubMed
  15. Int J Cardiol Heart Vasc. 2015 Apr 08;7:141-145 - PubMed
  16. Heart. 2002 Sep;88(3):249-54 - PubMed
  17. Ann Thorac Cardiovasc Surg. 2021 Oct 20;27(5):332-334 - PubMed
  18. J Am Coll Cardiol. 2009 Jan 20;53(3):284-91 - PubMed
  19. J Hum Hypertens. 2011 Oct;25(10):578-84 - PubMed
  20. J Am Coll Cardiol. 1998 Sep;32(3):695-703 - PubMed
  21. J Am Coll Cardiol. 2009 Jun 30;54(1):36-46 - PubMed
  22. Am J Med. 2003 Jul;115(1):41-6 - PubMed
  23. Hypertension. 1988 May;11(5):457-63 - PubMed
  24. J Am Coll Cardiol. 2007 Jan 16;49(2):198-207 - PubMed
  25. Am J Cardiol. 2011 Nov 1;108(9):1283-8 - PubMed
  26. Heart. 2010 Jun;96(12):948-55 - PubMed
  27. Circulation. 1996 Jan 15;93(2):259-65 - PubMed
  28. Int J Cardiol Heart Vasc. 2015 Jan 09;9:43-47 - PubMed
  29. Int J Cardiol. 2010 Nov 19;145(2):367-368 - PubMed
  30. Circ Cardiovasc Imaging. 2013 Mar 1;6(2):262-7 - PubMed
  31. JACC Heart Fail. 2017 Aug;5(8):543-551 - PubMed
  32. Echocardiography. 2008 Apr;25(4):424-8 - PubMed
  33. J Hypertens. 2006 Apr;24(4):767-73 - PubMed
  34. Hypertension. 2010 Jan;55(1):1-8 - PubMed
  35. Lancet. 2002 Dec 14;360(9349):1903-13 - PubMed
  36. Am J Cardiol. 2008 Sep 1;102(5):616-20 - PubMed
  37. J Am Soc Echocardiogr. 2004 Jul;17(7):717-22 - PubMed
  38. Int J Cardiol Heart Vasc. 2015 Apr 09;7:149-150 - PubMed
  39. J Appl Physiol (1985). 2019 Feb 1;126(2):354-362 - PubMed
  40. Eur J Heart Fail. 2009 Sep;11(9):855-62 - PubMed
  41. Am J Cardiol. 2000 Apr 15;85(8):1035-8 - PubMed
  42. N Engl J Med. 2008 Dec 4;359(23):2456-67 - PubMed
  43. N Engl J Med. 2006 Apr 20;354(16):1685-97 - PubMed
  44. J Hum Hypertens. 2006 Aug;20(8):628-30 - PubMed
  45. Circulation. 2001 Jul 17;104(3):286-91 - PubMed
  46. Angiology. 2004 May-Jun;55(3):295-301 - PubMed
  47. J Card Fail. 2007 Oct;13(8):649-55 - PubMed
  48. Chest. 1978 Apr;73(4):466-70 - PubMed
  49. Circ Cardiovasc Imaging. 2013 Sep;6(5):e28 - PubMed
  50. Circulation. 1998 Nov 24;98(21):2282-9 - PubMed
  51. J Hypertens. 2021 Jul 1;39(7):1421-1428 - PubMed
  52. Eur Heart J. 2007 Oct;28(20):2539-50 - PubMed
  53. Int J Cardiol. 2010 Aug 6;143(1):e1-3 - PubMed
  54. Circulation. 2002 Mar 12;105(10):1195-201 - PubMed
  55. Metabolism. 2008 Oct;57 Suppl 2:S36-9 - PubMed

Publication Types