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Martínez-Campayo N, Paradela de la Morena S, Pértega-Díaz S, et al. Survival of Women Previously Diagnosed of Melanoma with Subsequent Pregnancy: A Systematic Review and Meta-Analysis and a Single-Center Experience. J Clin Med. 2021;11(1)doi: 10.3390/jcm11010083.
Martínez-Campayo, N., Paradela de la Morena, S., Pértega-Díaz, S., Iglesias Pena, L., Vihinen, P., Mattila, K., Lens, M. B., Tejera-Vaquerizo, A., & Fonseca, E. (2021). Survival of Women Previously Diagnosed of Melanoma with Subsequent Pregnancy: A Systematic Review and Meta-Analysis and a Single-Center Experience. Journal of clinical medicine, 11(1), . https://doi.org/10.3390/jcm11010083
Martínez-Campayo, Nieves, et al. "Survival of Women Previously Diagnosed of Melanoma with Subsequent Pregnancy: A Systematic Review and Meta-Analysis and a Single-Center Experience." Journal of clinical medicine vol. 11,1 (2021). doi: https://doi.org/10.3390/jcm11010083
Martínez-Campayo N, Paradela de la Morena S, Pértega-Díaz S, Iglesias Pena L, Vihinen P, Mattila K, Lens MB, Tejera-Vaquerizo A, Fonseca E. Survival of Women Previously Diagnosed of Melanoma with Subsequent Pregnancy: A Systematic Review and Meta-Analysis and a Single-Center Experience. J Clin Med. 2021 Dec 24;11(1). doi: 10.3390/jcm11010083. PMID: 35011822; PMCID: PMC8745217.
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J Clin Med. 2021 Dec 24;11(1). doi: 10.3390/jcm11010083.

Survival of Women Previously Diagnosed of Melanoma with Subsequent Pregnancy: A Systematic Review and Meta-Analysis and a Single-Center Experience.

Journal of clinical medicine

Nieves Martínez-Campayo, Sabela Paradela de la Morena, Sonia Pértega-Díaz, Luisa Iglesias Pena, Pia Vihinen, Kalle Mattila, Marko B Lens, Antonio Tejera-Vaquerizo, Eduardo Fonseca

Affiliations

  1. Department of Dermatology, University Hospital of A Coruña, 15006 Corunna, Spain.
  2. Department of Research, University Hospital of A Coruña, 15006 Corunna, Spain.
  3. FICAN West Cancer Centre and Department of Oncology, Turku University Hospital and University of Turku, 20521 Turku, Finland.
  4. Genetic Epidemiology Division, Cancer Research UK, St. James's University Hospital, Beckett St., Leeds LS9 7TF, UK.
  5. Department of Dermatology, Dermatologic Institute GlobalDerm, Palma del Río, 14700 Cordova, Spain.
  6. Unit of Cutaneous Oncology, San Juan de Dios Hospital, 14012 Cordova, Spain.

PMID: 35011822 PMCID: PMC8745217 DOI: 10.3390/jcm11010083

Abstract

Melanoma incidence has increased over the last few decades. How the prognosis of a previously diagnosed melanoma may be affected by a woman's subsequent pregnancy has been debated in the literature since the 1950s, and the outcomes are essential to women who are melanoma survivors in their childbearing years. The main objective of this systematic review is to improve the understanding of whether the course of melanoma in a woman may be altered by a subsequent pregnancy and to help clinicians' diagnosis. Eligible studies for the systematic review were clinical trials, observational cohort studies and case-control studies that compared prognosis outcomes for non-pregnant patients with melanoma, or pregnant before melanoma diagnosis, versus pregnant patients after a diagnosis of melanoma. The search strategy yielded 1101 articles, of which 4 met the inclusion criteria for the systematic review. All the studies were retrospective non-randomised cohorts with patients with melanomas diagnosed before pregnancy. According to our findings, a subsequent pregnancy was not a significant influence on the outcome of a previous melanoma. However, given the small number of identified studies and the heterogeneous data included, it is recommended to approach these patients with caution, and counselling should be given by known prognostic factors. We also reviewed the medical records of 84 patients of childbearing age (35.8 ± 6.3 years, range 21-45 years) who were diagnosed with cutaneous invasive melanoma in our hospital between 2008 and 2018 (N = 724). Of these, 11 (13.1%) had a pregnancy after melanoma diagnosis (age at pregnancy: 35.6 ± 6.3 years). No statistical differences in outcome were detected.

Keywords: melanoma; meta-analysis; pregnancy; prognosis; survival; systematic review

References

  1. CA Cancer J Clin. 2001 Jan-Feb;51(1):15-36 - PubMed
  2. J Clin Oncol. 2009 Jul 1;27(19):e11-2; author reply e13-4 - PubMed
  3. Dermatol Surg. 2015 Aug;41(8):875-82 - PubMed
  4. J Am Acad Dermatol. 2011 Nov;65(5):1032-47 - PubMed
  5. Cancer Causes Control. 2008 Jun;19(5):437-42 - PubMed
  6. Actas Dermosifiliogr. 2013 Nov;104(9):789-99 - PubMed
  7. Cancer Epidemiol Biomarkers Prev. 2006 Jan;15(1):65-9 - PubMed
  8. J Am Acad Dermatol. 2019 Jan;80(1):208-250 - PubMed
  9. J Am Acad Dermatol. 2016 Oct;75(4):669-678 - PubMed
  10. Transpl Int. 2018 Feb;31(2):125-130 - PubMed
  11. J Clin Oncol. 2009 Jan 1;27(1):45-51 - PubMed
  12. Cancer Epidemiol Biomarkers Prev. 2019 Nov;28(11):1857-1860 - PubMed
  13. Eur J Cancer. 2020 Feb;126:141-158 - PubMed
  14. Obstet Med. 2017 Sep;10(3):107-112 - PubMed
  15. Lancet. 1994 Jun 25;343(8913):1587-9 - PubMed
  16. Cancer. 1951 Mar;4(2):324-34 - PubMed
  17. Int J Womens Dermatol. 2018 Mar 01;4(2):113-115 - PubMed
  18. J Clin Oncol. 2004 Nov 1;22(21):4369-75 - PubMed
  19. Obstet Gynecol Surv. 2002 Feb;57(2):112-9 - PubMed
  20. Int J Surg. 2014 Dec;12(12):1495-9 - PubMed
  21. Acta Oncol. 2012 May;51(5):662-8 - PubMed

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