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J Clin Med. 2021 Dec 29;11(1). doi: 10.3390/jcm11010177.

Influence of Overhanging Bleb on Corneal Higher-Order Aberrations after Trabeculectomy.

Journal of clinical medicine

Yu Mizuno, Kazuyuki Hirooka, Yoshiaki Kiuchi

Affiliations

  1. Department of Ophthalmology and Visual Science, Hiroshima University, 1-2-3 Kasumi Minamiku, Hiroshima 734-8551, Japan.

PMID: 35011917 PMCID: PMC8745328 DOI: 10.3390/jcm11010177

Abstract

Recent advances in ocular aberrometry have revealed that ocular surgery increases ocular and corneal higher-order aberrations. This retrospective single-center study aimed to examine the effects of the overhanging bleb on corneal higher-order aberrations using a wavefront analyzer. We included 61 eyes from 50 patients with overhanging bleb after trabeculectomy with a fornix-based conjunctival flap using mitomycin C (overhanging bleb group) and 65 eyes from 54 glaucoma patients with no history of glaucoma surgery (control group). Corneal higher-order aberrations (total higher-order aberrations, coma aberrations, coma-like aberrations, spherical aberrations, and spherical-like aberrations) on a 4 mm pupil diameter were measured using the TOPCON KR-1W wavefront analyzer. Corneal coma aberrations were higher in the overhanging bleb group than in the control group (0.16 ± 0.13 μm and 0.10 ± 0.05 μm, respectively;

Keywords: glaucoma; higher-order aberrations; mitomycin C; overhanging bleb; trabeculectomy

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