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mSphere. 2022 Jan 05;e0087421. doi: 10.1128/msphere.00874-21. Epub 2022 Jan 05.

The Protective Role of 1,8-Dihydroxynaphthalene-Melanin on Conidia of the Opportunistic Human Pathogen Aspergillus fumigatus Revisited: No Role in Protection against Hydrogen Peroxide and Superoxides.

mSphere

E M Keizer, I D Valdes, B L McCann, E M Bignell, H A B Wösten, H de Cock

Affiliations

  1. Microbiology, Department of Biology, Utrecht Universitygrid.5477.1, Utrecht, the Netherlands.
  2. Institute of Biomembranes, Utrecht Universitygrid.5477.1, Utrecht, the Netherlands.
  3. MRC Centre for Medical Mycology, University of Exeter, Exerter, United Kingdom.

PMID: 34986316 PMCID: PMC8730813 DOI: 10.1128/msphere.00874-21

Abstract

Previously, 1,8-dihydroxynaphthalene (DHN)-melanin was described to protect Aspergillus fumigatus against hydrogen peroxide (H

Keywords: Aspergillus fumigatus; DHN-melanin; catalase; conidia; hydrogen peroxide; reactive oxygen species

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