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Urologe A. 2022 Jan;61(1):41-51. doi: 10.1007/s00120-021-01621-6. Epub 2021 Aug 23.

[Urinary bladder microbiome analysis and probiotic treatment options for women with recurrent urinary tract infections].

Der Urologe. Ausg. A

[Article in German]
T Schiereck, S Yeldan, J Kranz, L Schneidewind, F Wagenlehner, I Wieters, M J G T Vehreschild, T Otto, D Barski

Affiliations

  1. Urologische Klinik, Lukaskrankenhaus Neuss, Rheinland Klinikum, Preussenstr. 84, 41464, Neuss, Deutschland. [email protected].
  2. Urologische Klinik, Lukaskrankenhaus Neuss, Rheinland Klinikum, Preussenstr. 84, 41464, Neuss, Deutschland.
  3. Klinik für Urologie und Kinderurologie, St.-Antonius-Hospital Eschweiler, Akademisches Lehrkrankenhaus der RWTH Aachen, Eschweiler, Deutschland.
  4. Universitätsklinik und Poliklinik für Urologie, Universitätsklinikum Halle (Saale), Halle (Saale), Deutschland.
  5. Urologische Klinik und Poliklinik, Universitätsmedizin Rostock, Ernst-Heydemann-Str. 6, 18055, Rostock, Deutschland.
  6. Klinik für Urologie, Kinderurologie und Andrologie, Universitätsklinikum Gießen, Gießen, Deutschland.
  7. Zentrum für Innere Medizin, Infektiologie, Universitätsklinikum Frankfurt, Goethe Universität Frankfurt, Frankfurt am Main, Deutschland.
  8. Universität Duisburg-Essen, Essen, Deutschland.

PMID: 34424357 PMCID: PMC8381347 DOI: 10.1007/s00120-021-01621-6

Abstract

Novel preventive measures and therapeutic approaches are needed to reduce the frequency of recurrent urinary tract infections (rUTI) and the associated emergence of multidrug-resistant uropathogens. The aim of this review is to systematically present the available evidence on the urinary bladder microbiome of healthy women and those with rUTIs. In addition, relevant studies on the efficacy of probiotics in rUTIs are presented in a structured manner. This will provide an overview on the current state of research and an outlook on treatment strategies beyond the usual antimicrobial options.

© 2021. Springer Medizin Verlag GmbH, ein Teil von Springer Nature.

Keywords: 16S-rRNA-sequencing; Fecal microbiota transplantation; Female bladder; Lactobacillus; Multidrug-resistant pathogens

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