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Contact Dermatitis. 2022 Feb;86(2):123-125. doi: 10.1111/cod.13984. Epub 2021 Oct 13.

Mepolizumab for treating systemic allergic dermatitis with hypereosinophilia likely secondary to a nickel/cobalt-containing coronary artery stent.

Contact dermatitis

Paul Faybusovich, Jordan Lim, Michael D Ioffreda, Taha Al-Shaikhly

Affiliations

  1. Section of Allergy, Asthma & Immunology, Department of Medicine, Penn State College of Medicine, Hershey, Pennsylvania, USA.
  2. Department of Dermatology, Penn State College of Medicine, Hershey, Pennsylvania, USA.

PMID: 34596911 DOI: 10.1111/cod.13984

[No abstract available.]

Keywords: case report; cobalt; drug-eluting stent; hypereosinophilia; interleukin 5 (IL-5); medical device; mepolizumab; nickel; systemic allergic dermatitis

References

  1. Joshi SR, Khan DA. Effective use of dupilumab in managing systemic allergic contact dermatitis. Dermatitis. 2018;29(5):282-284. https://doi.org/10.1097/der.0000000000000409 - PubMed
  2. Frings VG, Böer-Auer A, Breuer K. Histomorphology and immunophenotype of eczematous skin lesions revisited-skin biopsies are not reliable in differentiating allergic contact dermatitis, irritant contact dermatitis, and atopic dermatitis. Am J Dermatopathol. 2018;40(1):7-16. https://doi.org/10.1097/dad.0000000000000842 - PubMed
  3. Haussmann J, Pratt M, Linett L, Zimmerman D. Allergic contact dermatitis and eosinophilia in association with a hemodialysis cannula. Am J Kidney Dis. 2005;45(2):e23-e26. https://doi.org/10.1053/j.ajkd.2004.11.003 - PubMed
  4. Jensen CS, Lisby S, Larsen JK, Veien NK, Menné T. Characterization of lymphocyte subpopulations and cytokine profiles in peripheral blood of nickel-sensitive individuals with systemic contact dermatitis after oral nickel exposure. Contact Dermatitis. 2004;50(1):31-38. https://doi.org/10.1111/j.0105-1873.2004.00294.x - PubMed

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