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Brada SA, Egan TD, Viscomi CM. The use of remifentanil infusion to facilitate epidural catheter placement in a parturient: a case report with pharmacokinetic simulations. Int J Obstet Anesth. 1998;7(2):124-7doi: 10.1016/s0959-289x(98)90009-7.
Brada, S. A., Egan, T. D., & Viscomi, C. M. (1998). The use of remifentanil infusion to facilitate epidural catheter placement in a parturient: a case report with pharmacokinetic simulations. International journal of obstetric anesthesia, 7(2), 124-7. https://doi.org/10.1016/s0959-289x(98)90009-7
Brada, S A, et al. "The use of remifentanil infusion to facilitate epidural catheter placement in a parturient: a case report with pharmacokinetic simulations." International journal of obstetric anesthesia vol. 7,2 (1998): 124-7. doi: https://doi.org/10.1016/s0959-289x(98)90009-7
Brada SA, Egan TD, Viscomi CM. The use of remifentanil infusion to facilitate epidural catheter placement in a parturient: a case report with pharmacokinetic simulations. Int J Obstet Anesth. 1998 Apr;7(2):124-7. doi: 10.1016/s0959-289x(98)90009-7. PMID: 15321230.
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Int J Obstet Anesth. 1998 Apr;7(2):124-7. doi: 10.1016/s0959-289x(98)90009-7.

The use of remifentanil infusion to facilitate epidural catheter placement in a parturient: a case report with pharmacokinetic simulations.

International journal of obstetric anesthesia

S A Brada, T D Egan, C M Viscomi

Affiliations

  1. Department of Anesthesiology, University of Utah Medical Center, 50 North Medical Drive, Salt Lake City, UT 84132, USA.

PMID: 15321230 DOI: 10.1016/s0959-289x(98)90009-7

Abstract

We present a case in which remifentanil infusion was used to provide analgesia during epidural catheter placement in a parturient who was experiencing great difficulty staying motionless because of extremely painful uterine contractions. Remifentanil may provide certain advantages in this setting, including improved analgesia during the procedure, briefer residual maternal and fetal (or newborn) drug effects after the procedure, and greater technical ease of catheter placement because of decreased movement induced by pain. Pharmacokinetic simulation of the dose administered suggests that analgesic effect-site concentrations can be rapidly produced, and that these concentrations decline rapidly to clinically insignificant levels after the infusion.

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