Display options
Cite
Soboleva EL, Gabbasov ZA, Agapov AA, et al. Circulating bone marrow stem/progenitor cells in vascular atherogenesis and in the noninvasive diagnosis of coronary stenosis. Exp Clin Cardiol. 2005;10(3):184-8
Soboleva, E. L., Gabbasov, Z. A., Agapov, A. A., Akchurin, R. S., Saburova, O. S., Romanov, Y. A., & Smirnov, V. N. (2005). Circulating bone marrow stem/progenitor cells in vascular atherogenesis and in the noninvasive diagnosis of coronary stenosis. Experimental and clinical cardiology, 10(3), 184-8.
Soboleva, Emma L, et al. "Circulating bone marrow stem/progenitor cells in vascular atherogenesis and in the noninvasive diagnosis of coronary stenosis." Experimental and clinical cardiology vol. 10,3 (2005): 184-8.
Soboleva EL, Gabbasov ZA, Agapov AA, Akchurin RS, Saburova OS, Romanov YA, Smirnov VN. Circulating bone marrow stem/progenitor cells in vascular atherogenesis and in the noninvasive diagnosis of coronary stenosis. Exp Clin Cardiol. 2005;10(3):184-8. PMID: 19641685; PMCID: PMC2716249.
Copy Download .nbib Format: NLM
Share it on

Exp Clin Cardiol. 2005;10(3):184-8.

Circulating bone marrow stem/progenitor cells in vascular atherogenesis and in the noninvasive diagnosis of coronary stenosis.

Experimental and clinical cardiology

Emma L Soboleva, Zufar A Gabbasov, Alexander A Agapov, Renat S Akchurin, Olga S Saburova, Yury A Romanov, Vladimir N Smirnov

Affiliations

  1. Cardiology Research Center, Moscow, Russia.

PMID: 19641685 PMCID: PMC2716249

Abstract

Using autopsy specimens and clonal technique, the authors showed that hematopoietic and stromal stem colony-forming units are present in human atheromatous vascular intima. Stromal colony-forming units were also detected in the mononuclear fraction of the blood of patients with hyperlipidemia and coronary stenosis, and were not found in the peripheral blood of normolipidemic volunteers. Using flow cytometry, the absence of stromal circulating colony-forming units in healthy volunteers and their presence in coronary patients was confirmed. It was thought that the presence of circulating stromal precursors with a certain phenotype and variations in their level in blood could serve as an informative noninvasive indicator of coronary stenosis.

Keywords: Atherosclerosis; Hematopoietic and stromal colony-forming units; Stem/progenitor cells

References

  1. J Hematother. 1996 Jun;5(3):213-26 - PubMed
  2. J Biol Chem. 1974 Aug 25;249(16):5153-62 - PubMed
  3. Cell Tissue Kinet. 1985 Nov;18(6):589-95 - PubMed
  4. J Vasc Res. 2001 Mar-Apr;38(2):113-9 - PubMed
  5. Nat Med. 2002 Apr;8(4):403-9 - PubMed
  6. Nature. 1982 Jul 15;298(5871):280-3 - PubMed
  7. J Cell Biol. 2001 May 28;153(5):1133-40 - PubMed
  8. Cell Tissue Kinet. 1970 Oct;3(4):393-403 - PubMed
  9. Science. 1998 Mar 6;279(5356):1528-30 - PubMed
  10. Blood. 1979 Aug;54(2):485-500 - PubMed
  11. Proc Natl Acad Sci U S A. 1990 Jun;87(12):4600-4 - PubMed
  12. Proc Natl Acad Sci U S A. 1973 Jun;70(6):1753-6 - PubMed
  13. Ann N Y Acad Sci. 1995 Jan 17;748:12-37; discussion 37-9 - PubMed
  14. Nat Med. 2002 Nov;8(11):1249-56 - PubMed
  15. Ann N Y Acad Sci. 2001 Dec;947:18-24; discussion 24-5 - PubMed
  16. Science. 1997 Apr 4;276(5309):71-4 - PubMed
  17. Paroi Arterielle. 1981;7(3):107-12 - PubMed
  18. Biull Eksp Biol Med. 1989 May;107(5):600-4 - PubMed
  19. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4754-9 - PubMed
  20. Nature. 1993 Apr 29;362(6423):801-9 - PubMed
  21. Blood. 1991 Jul 1;78(1):55-62 - PubMed

Publication Types