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J Res Med Sci. 2011 Apr;16(4):568-73.

Metastatic medullary thyroid carcinoma: A case report.

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences

Mitra Niafar, Shahram Dabiri, Farshid Bozorgi, Farid Niafar, Nasrin Gholami

Affiliations

  1. Assistant Professor, Endocrinology and Metabolism Section, Department of Medicine, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.

PMID: 22091276 PMCID: PMC3214365

Abstract

Medullary thyroid carcinoma accounts for 4% of thyroid carcinoma and originates from parafollicular cells, secreting calcitonin and carcinoembryonic antigen (CEA). Conventional radiographic modalities such as Computerized Tomography (CT), Magnetic Resonance Imaging (MRI), and Ultrasonography (U/S), are used for detecting recurrences following total thyroidectomy. However, metastatic disease frequently escapes detection by the above modalities, even when its presence is suggested by persistently elevated serum calcitonin levels. In this paper, we report a case of medullary thyroid carcinoma in a 40 year-old woman who had whole body octreotide scintigraphy to evaluate and detect the origin of calcitonin and CEA secretion.

Keywords: Calcitonin; Medullary; Neoplasm metastasis; Thyroid cancer

References

  1. Rays. 2000 Apr-Jun;25(2):273-82 - PubMed
  2. Surgery. 1993 Dec;114(6):1083-9 - PubMed
  3. Cancer Res. 2002 Dec 15;62(24):7284-90 - PubMed
  4. Semin Surg Oncol. 1999 Jan-Feb;16(1):50-63 - PubMed
  5. J Intern Med. 1998 Jun;243(6):521-6 - PubMed
  6. J Clin Oncol. 2006 Apr 10;24(11):1653-5 - PubMed
  7. Q J Nucl Med. 2001 Jun;45(2):189-200 - PubMed
  8. Cancer Biother Radiopharm. 2004 Apr;19(2):211-7 - PubMed
  9. J Clin Endocrinol Metab. 2001 Oct;86(10):4965-9 - PubMed
  10. Medicine (Baltimore). 1984 Nov;63(6):319-42 - PubMed
  11. Eur J Nucl Med Mol Imaging. 2007 Oct;34(10):1635-45 - PubMed
  12. Thyroid. 2009 Jun;19(6):565-612 - PubMed
  13. J Clin Endocrinol Metab. 1984 Dec;59(6):1148-51 - PubMed
  14. Cancer. 1979 Mar;43(3):825-37 - PubMed
  15. J Nucl Med. 2003 May;44(5):708-16 - PubMed
  16. J Postgrad Med. 1995 Jan-Mar;41(1):12-3 - PubMed
  17. Endocr Relat Cancer. 2004 Jun;11(2):357-63 - PubMed
  18. Best Pract Res Clin Endocrinol Metab. 2001 Jun;15(2):225-39 - PubMed
  19. Eur J Nucl Med. 2000 Sep;27(9):1318-25 - PubMed
  20. Endocrinol Metab Clin North Am. 2007 Sep;36(3):823-37, viii - PubMed
  21. Cancer Res. 2004 Oct 1;64(19):7099-109 - PubMed

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