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Ginghină C, Botezatu CD, Șerban M, et al. A personalized medicine target: heart failure in women. J Med Life. 2011;4(3):280-6
Ginghină, C., Botezatu, C. D., Șerban, M., & Jurcuţ, R. (2011). A personalized medicine target: heart failure in women. Journal of medicine and life, 4(3), 280-6.
Ginghină, C, et al. "A personalized medicine target: heart failure in women." Journal of medicine and life vol. 4,3 (2011): 280-6.
Ginghină C, Botezatu CD, Șerban M, Jurcuţ R. A personalized medicine target: heart failure in women. J Med Life. 2011 Aug 15;4(3):280-6. Epub 2011 Aug 25. PMID: 22567052; PMCID: PMC3168816.
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J Med Life. 2011 Aug 15;4(3):280-6. Epub 2011 Aug 25.

A personalized medicine target: heart failure in women.

Journal of medicine and life

C Ginghină, C D Botezatu, M Șerban, R Jurcuţ

Affiliations

  1. Prof. Dr. C. C. Iliescu Institute of Cardiovascular Diseases, Cardiology Clinic, Bucharest, Romania. [email protected]

PMID: 22567052 PMCID: PMC3168816

Abstract

It is increasingly known that gender differences affect disease presentation, clinical pathways, diagnostic yield and prognosis of patients with cardiovascular disorders. There are novel insights regarding heart failure that provide a platform for personalized medicine. This is a review of the existent data about heart failure in women, a neglected topic that has gained considerable interest in the past years. Heart failure in women differs in many aspects from that of men. Part of the difference is attributable to age, ventricular function and cause of heart failure, with women being generally older at heart failure onset, more often without left ventricular systolic dysfunction and less often having heart failure due to ischaemic heart disease, in comparison with men. Elucidation of the genetic and pathophysiological basis of sex differences, together with clinical trials designed to study the impact of treatments in women, could lead to sex based heart failure management.

Keywords: cardiomiopathy; ejection fraction; heart failure; women

References

  1. Am J Cardiol. 1998 Jul 1;82(1):76-81 - PubMed
  2. Circulation. 2005 Oct 11;112(15):2254-62 - PubMed
  3. J Am Coll Cardiol. 1997 Apr;29(5):1074-80 - PubMed
  4. Am J Cardiol. 2002 Aug 1;90(3):254-8 - PubMed
  5. Eur J Clin Nutr. 2010 Jun;64(6):587-94 - PubMed
  6. Circulation. 2002 Dec 10;106(24):3068-72 - PubMed
  7. Circulation. 1999 May 4;99(17):2334-41 - PubMed
  8. J Am Coll Cardiol. 2006 Nov 7;48(9):1808-12 - PubMed
  9. Pediatr Cardiol. 2008 Jan;29(1):102-7 - PubMed
  10. Eur Heart J. 2010 May;31(10):1165-7 - PubMed
  11. Heart. 2010 Sep;96(17):1352-7 - PubMed
  12. Cardiology. 1990;77 Suppl 2:71-9 - PubMed
  13. Arch Intern Med. 1997 Nov 24;157(21):2460-4 - PubMed
  14. Heart. 2008 Mar;94(3):e10 - PubMed
  15. Eur Heart J. 2004 Jan;25(2):129-35 - PubMed
  16. Circulation. 2006 Jan 31;113(4):481-9 - PubMed
  17. Eur Heart J. 2010 May;31(10):1188-96 - PubMed
  18. Circulation. 1999 Apr 13;99(14):1816-21 - PubMed
  19. Eur Heart J. 2010 Nov;31(21):2677-87 - PubMed
  20. Eur Heart J. 2009 Mar;30(6):671-8 - PubMed
  21. Am J Cardiol. 1993 Aug 1;72(3):310-3 - PubMed
  22. Eur J Heart Fail. 2009 Mar;11(3):299-303 - PubMed
  23. Congest Heart Fail. 2005 May-Jun;11(3):163-6 - PubMed
  24. Arch Intern Med. 1994 Feb 28;154(4):417-23 - PubMed
  25. N Engl J Med. 2002 Aug 1;347(5):305-13 - PubMed
  26. Hypertension. 1999 Feb;33(2):676-80 - PubMed
  27. Eur Heart J. 2000 May;21(9):699-700 - PubMed
  28. Circulation. 2001 Jun 5;103(22):2668-73 - PubMed
  29. J Thorac Cardiovasc Surg. 2004 Jan;127(1):1-3 - PubMed
  30. Eur Heart J. 2003 Nov;24(22):2046-53 - PubMed
  31. Eur Heart J. 2007 Oct;28(20):2539-50 - PubMed
  32. Heart. 2006 May;92 Suppl 3:iii14-8 - PubMed

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