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Andrews E, Velupillai P, Sung CK, et al. Production of a natural antibody to the mouse polyoma virus is a multigenic trait. G3 (Bethesda). 2012;2(3):353-5doi: 10.1534/g3.111.001701.
Andrews, E., Velupillai, P., Sung, C. K., Beier, D. R., & Benjamin, T. (2012). Production of a natural antibody to the mouse polyoma virus is a multigenic trait. G3 (Bethesda, Md.), 2(3), 353-5. https://doi.org/10.1534/g3.111.001701
Andrews, Erik, et al. "Production of a natural antibody to the mouse polyoma virus is a multigenic trait." G3 (Bethesda, Md.) vol. 2,3 (2012): 353-5. doi: https://doi.org/10.1534/g3.111.001701
Andrews E, Velupillai P, Sung CK, Beier DR, Benjamin T. Production of a natural antibody to the mouse polyoma virus is a multigenic trait. G3 (Bethesda). 2012 Mar;2(3):353-5. doi: 10.1534/g3.111.001701. Epub 2012 Mar 01. PMID: 22413089; PMCID: PMC3291505.
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G3 (Bethesda). 2012 Mar;2(3):353-5. doi: 10.1534/g3.111.001701. Epub 2012 Mar 01.

Production of a natural antibody to the mouse polyoma virus is a multigenic trait.

G3 (Bethesda, Md.)

Erik Andrews, Palanivel Velupillai, Chang Kyoo Sung, David R Beier, Thomas Benjamin

PMID: 22413089 PMCID: PMC3291505 DOI: 10.1534/g3.111.001701

Abstract

MA/MyJ mice express a natural antibody to the highly oncogenic polyoma virus. C57BR/cdJ mice lack this antibody but mount an adaptive T-cell response to the virus. Analysis of F2 progeny of a cross between these strains reveals a pattern of inheritance of expression of the natural antibody involving two genes in an epistatic relationship.

Keywords: epistasis; multigenic inheritance; natural antibody; polyoma virus

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