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Riahinejad S, Pour AF, Dehghani L, et al. The comparative study of Yaz and Ovocept-ld on patients with simple ovarian cysts referring to Iran-Isfahan Shariati Hospital. Adv Biomed Res. 2014;3:205doi: 10.4103/2277-9175.142315.
Riahinejad, S., Pour, A. F., Dehghani, L., & Hajizadeh, S. (2014). The comparative study of Yaz and Ovocept-ld on patients with simple ovarian cysts referring to Iran-Isfahan Shariati Hospital. Advanced biomedical research, 3205. https://doi.org/10.4103/2277-9175.142315
Riahinejad, Soheyla, et al. "The comparative study of Yaz and Ovocept-ld on patients with simple ovarian cysts referring to Iran-Isfahan Shariati Hospital." Advanced biomedical research vol. 3 (2014): 205. doi: https://doi.org/10.4103/2277-9175.142315
Riahinejad S, Pour AF, Dehghani L, Hajizadeh S. The comparative study of Yaz and Ovocept-ld on patients with simple ovarian cysts referring to Iran-Isfahan Shariati Hospital. Adv Biomed Res. 2014 Oct 07;3:205. doi: 10.4103/2277-9175.142315. eCollection 2014. PMID: 25337535; PMCID: PMC4202506.
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Adv Biomed Res. 2014 Oct 07;3:205. doi: 10.4103/2277-9175.142315. eCollection 2014.

The comparative study of Yaz and Ovocept-ld on patients with simple ovarian cysts referring to Iran-Isfahan Shariati Hospital.

Advanced biomedical research

Soheyla Riahinejad, Azam Foroughi Pour, Leila Dehghani, Saadat Hajizadeh

Affiliations

  1. Department of Medical Sciences, Nursing and Midwifery College, Islamic Azad University, Najafabad Branch, Isfahan, Iran.
  2. Faculty of Midwifery Group, Nursing and Midwifery College, Islamic Azad University, Najafabad Branch, Isfahan, Iran.

PMID: 25337535 PMCID: PMC4202506 DOI: 10.4103/2277-9175.142315

Abstract

BACKGROUND: Functional ovarian cysts include follicular, corpus luteum, and theca lutein cysts are the most common adnexal masses (about 50%) in women of reproductive age. Treatment with the combined monophasic oral contraceptives reduces functional ovarian cysts. Yaz (drospirenone/ethinyl estradiol) is a low-dose combined oral contraceptive pill containing 20 μg ethinyl estradiol and 3 mg drospirenone. In addition to contraceptive effects, Yaz has anti-mineralocorticoid and anti-adrenergic effects. Ovocept- low-dose LD is also a low-dose combined oral contraceptive drug containing 30 μg ethinyl estradiol and 3 mg norgestrol. Ovocept-LD has some side-effects such as weight gain, spotting, breast tenderness, nausea, and headache.

MATERIALS AND METHODS: Being a clinical study, the present research was carried out on 42 patients with the simple ovarian cysts from 2010 to 2012. 84 Patients were assigned to A and B groups. Group A received Yaz once a day for a period of 28 days and group B received Ovocept-LD once a day for a period of 21 days. After treating by Yaz and Ovocept-LD, Cysts were evaluated by ultrasound. Results were analyzed by the SPSS software. A P < 0.05 was considered the significance threshold.

RESULTS: Obtained results indicated that both Yaz and Ovocept-LD had an effect on the simple ovarian cysts. Statistical tests, however, has shown that the effect of Yaz has been significantly more than that of Ovocept-LD.

CONCLUSION: Given the faster and better recovery effect, and the lesser side effects of Yaz as compared to Ovocept-LD, it is recommended to use Yaz for the simple ovarian cysts.

Keywords: Ovocept-LD; Yaz; simple ovarian cyst

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