Display options
Cite
Zétola AL, Verbicaro T, Littieri S, et al. Recombinant human bone morphogenetic protein type 2 in the reconstruction of atrophic maxilla: Case report with long-term follow-up. J Indian Soc Periodontol. 2014;18(6):781-5doi: 10.4103/0972-124X.147437.
Zétola, A. L., Verbicaro, T., Littieri, S., Larson, R., Giovanini, A. F., & Deliberador, T. M. (2014). Recombinant human bone morphogenetic protein type 2 in the reconstruction of atrophic maxilla: Case report with long-term follow-up. Journal of Indian Society of Periodontology, 18(6), 781-5. https://doi.org/10.4103/0972-124X.147437
Zétola, André Luiz, et al. "Recombinant human bone morphogenetic protein type 2 in the reconstruction of atrophic maxilla: Case report with long-term follow-up." Journal of Indian Society of Periodontology vol. 18,6 (2014): 781-5. doi: https://doi.org/10.4103/0972-124X.147437
Zétola AL, Verbicaro T, Littieri S, Larson R, Giovanini AF, Deliberador TM. Recombinant human bone morphogenetic protein type 2 in the reconstruction of atrophic maxilla: Case report with long-term follow-up. J Indian Soc Periodontol. 2014 Nov-Dec;18(6):781-5. doi: 10.4103/0972-124X.147437. PMID: 25624638; PMCID: PMC4296466.
Copy Download .nbib Format: NLM
Share it on

J Indian Soc Periodontol. 2014 Nov-Dec;18(6):781-5. doi: 10.4103/0972-124X.147437.

Recombinant human bone morphogenetic protein type 2 in the reconstruction of atrophic maxilla: Case report with long-term follow-up.

Journal of Indian Society of Periodontology

André Luiz Zétola, Thalyta Verbicaro, Sahara Littieri, Rafaela Larson, Allan Fernando Giovanini, Tatiana Miranda Deliberador

Affiliations

  1. Oral and Maxillofacial Surgeon, Chairman of Implantology, SOEPAR, Curitiba, PR, Brazil.
  2. Professor of Positivo University, Curitiba, PR, Brazil.
  3. Private Pratice, Curitiba, PR, Brazil.

PMID: 25624638 PMCID: PMC4296466 DOI: 10.4103/0972-124X.147437

Abstract

Autologous bone is reported by scientific literature as the gold standard for the replacement of the bone loss in maxillary atrophic area. Notwithstanding, this grafting type shows several disadvantages as: The procedure morbidity, limited size of the graft and longer recovering time. Recombinant human bone morphogenetic protein type 2 (rhBMP-2) has been used as bone substitute for the reconstruction of large bone defects. The aim of this case was to report a clinical case exhibiting the reconstruction of the atrophic maxilla through using rhBMP-2 as grafting material associated with absorbable collagen sponge (ACS). At 8 months of following-up, osseointegrated implants were placed. After 2 years and 5 months of following-up, it could be observed an appropriate aesthetical and functional rehabilitation.

Keywords: Bone regeneration; bone transplantation; dental implants; intercellular signaling peptides and proteins

References

  1. Int J Biol Sci. 2012;8(2):272-88 - PubMed
  2. Biomaterials. 2005 May;26(14):1829-35 - PubMed
  3. J Craniofac Surg. 2010 Nov;21(6):1894-6 - PubMed
  4. Int J Oral Maxillofac Implants. 2013 Sep-Oct;28(5):e243-51 - PubMed
  5. Science. 1965 Nov 12;150(3698):893-9 - PubMed
  6. J Oral Maxillofac Surg. 2007 Nov;65(11):2136-41 - PubMed
  7. Int J Oral Maxillofac Implants. 2013 Sep-Oct;28(5):e272-6 - PubMed
  8. Endocr Rev. 2000 Aug;21(4):393-411 - PubMed
  9. Braz J Med Biol Res. 2005 Oct;38(10):1463-73 - PubMed
  10. PLoS One. 2007 Jun 13;2(6):e514 - PubMed
  11. Biotechnol Lett. 2009 Dec;31(12):1825-35 - PubMed
  12. Implant Dent. 2013 Jun;22(3):232-7 - PubMed
  13. Int J Periodontics Restorative Dent. 2012 Feb;32(1):61-7 - PubMed
  14. J Oral Maxillofac Surg. 2009 Sep;67(9):1947-60 - PubMed
  15. J Craniofac Surg. 2009 Sep;20 Suppl 2:1759-64 - PubMed
  16. J Periodontol. 2014 Apr;85(4):525-35 - PubMed

Publication Types