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Ogretmen Z, Askin U, Hiz MM, et al. Triggering drug use in patients with psoriasis: an investigative report from Turkey. Postepy Dermatol Alergol. 2014;31(5):294-8doi: 10.5114/pdia.2014.44019.
Ogretmen, Z., Askin, U., Hiz, M. M., & Cevizci, S. (2014). Triggering drug use in patients with psoriasis: an investigative report from Turkey. Postepy dermatologii i alergologii, 31(5), 294-8. https://doi.org/10.5114/pdia.2014.44019
Ogretmen, Zerrin, et al. "Triggering drug use in patients with psoriasis: an investigative report from Turkey." Postepy dermatologii i alergologii vol. 31,5 (2014): 294-8. doi: https://doi.org/10.5114/pdia.2014.44019
Ogretmen Z, Askin U, Hiz MM, Cevizci S. Triggering drug use in patients with psoriasis: an investigative report from Turkey. Postepy Dermatol Alergol. 2014 Oct;31(5):294-8. doi: 10.5114/pdia.2014.44019. Epub 2014 Oct 22. PMID: 25395925; PMCID: PMC4221355.
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Postepy Dermatol Alergol. 2014 Oct;31(5):294-8. doi: 10.5114/pdia.2014.44019. Epub 2014 Oct 22.

Triggering drug use in patients with psoriasis: an investigative report from Turkey.

Postepy dermatologii i alergologii

Zerrin Ogretmen, Ulku Askin, Meliha Merve Hiz, Sibel Cevizci

Affiliations

  1. Department of Dermatology, School of Medicine, Çanakkale Onsekiz Mart University, Canakkale, Turkey. Head of Department: Prof. Zerrin Ö?retmen MD.
  2. Department of Dermatology, Baskent University Zübeyde Han?m Training and Research Center, Izmir, Turkey. Head of Department: Prof. Tülin Güleç MD.
  3. Department of Biology, The Faculty of Arts and Sciences, Canakkale Onsekiz Mart University, Canakkale, Turkey. Head of Department: Prof. ?smet Uysal PhD.
  4. Department of Public Health, School of Medicine, Canakkale Onsekiz Mart University, Canakkale, Turkey. Head of Department: Assoc. Prof. Ço?kun Bakar MD.

PMID: 25395925 PMCID: PMC4221355 DOI: 10.5114/pdia.2014.44019

Abstract

INTRODUCTION: The patients clinically diagnosed with psoriasis were investigated for drug use that may trigger psoriasis.

AIM: To minimize the triggering drug use and help the medical treatment of psoriasis patients.

MATERIAL AND METHODS: The study involved 289 psoriatic patients who attended our clinic in 2010-2012 and were asked to bring their drug lists of the last year, which they obtained from the pharmacy's record system. They were advised not to use the drugs that may trigger psoriasis. Data analyses were performed using SPSS program version 19.0.

RESULTS: A total of 289 patients were included in the study. Two hundred and twenty-one patients were using non-steroidal anti-inflammatory drugs; 133 patients were using anti-reflux drugs; 35 patients were using antidiabetic drugs; 31 patients were using calcium-channel blockers and 24 patients were using β-blockers. In our study group, there was no significantly difference between median PASI scores of the patients using a triggering drug and those of who are not using a triggering drug. However, there was a positive low correlation between PASI rates and numbers of drugs used (r = 0.180, p = 0.013).

CONCLUSIONS: Many other factors may trigger psoriasis, therefore the effect of stopping or minimizing the drug use on disease remission is not known. Because of the high triggering drug use rate, it is important to enlighten psoriasis patients about triggering drugs.

Keywords: non-steroidal anti-inflammatory drugs; psoriasis; triggering drugs; β-blockers

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