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Badenes R, Lozano A, Belda FJ. Postoperative pulmonary dysfunction and mechanical ventilation in cardiac surgery. Crit Care Res Pract. 2015;2015:420513doi: 10.1155/2015/420513.
Badenes, R., Lozano, A., & Belda, F. J. (2015). Postoperative pulmonary dysfunction and mechanical ventilation in cardiac surgery. Critical care research and practice, 2015420513. https://doi.org/10.1155/2015/420513
Badenes, Rafael, et al. "Postoperative pulmonary dysfunction and mechanical ventilation in cardiac surgery." Critical care research and practice vol. 2015 (2015): 420513. doi: https://doi.org/10.1155/2015/420513
Badenes R, Lozano A, Belda FJ. Postoperative pulmonary dysfunction and mechanical ventilation in cardiac surgery. Crit Care Res Pract. 2015;2015:420513. doi: 10.1155/2015/420513. Epub 2015 Feb 03. PMID: 25705516; PMCID: PMC4332756.
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Crit Care Res Pract. 2015;2015:420513. doi: 10.1155/2015/420513. Epub 2015 Feb 03.

Postoperative pulmonary dysfunction and mechanical ventilation in cardiac surgery.

Critical care research and practice

Rafael Badenes, Angels Lozano, F Javier Belda

Affiliations

  1. Department of Anesthesiology and Surgical Intensive Care, Hospital Clinic Universitari de Valencia, University of Valencia, 46010 Valencia, Spain.

PMID: 25705516 PMCID: PMC4332756 DOI: 10.1155/2015/420513

Abstract

Postoperative pulmonary dysfunction (PPD) is a frequent and significant complication after cardiac surgery. It contributes to morbidity and mortality and increases hospitalization stay and its associated costs. Its pathogenesis is not clear but it seems to be related to the development of a systemic inflammatory response with a subsequent pulmonary inflammation. Many factors have been described to contribute to this inflammatory response, including surgical procedure with sternotomy incision, effects of general anesthesia, topical cooling, and extracorporeal circulation (ECC) and mechanical ventilation (VM). Protective ventilation strategies can reduce the incidence of atelectasis (which still remains one of the principal causes of PDD) and pulmonary infections in surgical patients. In this way, the open lung approach (OLA), a protective ventilation strategy, has demonstrated attenuating the inflammatory response and improving gas exchange parameters and postoperative pulmonary functions with a better residual functional capacity (FRC) when compared with a conventional ventilatory strategy. Additionally, maintaining low frequency ventilation during ECC was shown to decrease the incidence of PDD after cardiac surgery, preserving lung function.

References

  1. Anesthesiology. 2011 May;114(5):1102-10 - PubMed
  2. Intensive Care Med. 1994;20(3):174-80 - PubMed
  3. Am Rev Respir Dis. 1988 May;137(5):1159-64 - PubMed
  4. Cardiovasc Eng. 2009 Mar;9(1):1-5 - PubMed
  5. Chest. 1989 Feb;95(2):424-34 - PubMed
  6. J Cardiothorac Vasc Anesth. 2012 Jun;26(3):443-7 - PubMed
  7. Interact Cardiovasc Thorac Surg. 2008 Feb;7(1):14-7 - PubMed
  8. JAMA. 1999 Jul 7;282(1):54-61 - PubMed
  9. Anesthesiology. 2008 Jan;108(1):46-54 - PubMed
  10. Crit Care Med. 1999 Apr;27(4):779-83 - PubMed
  11. Anaesthesiol Intensive Ther. 2013 Jul-Sep;45(3):164-70 - PubMed
  12. Am J Respir Crit Care Med. 1998 Jan;157(1):294-323 - PubMed
  13. Anesthesiology. 2012 May;116(5):1072-82 - PubMed
  14. BMJ Open. 2014 Jun 24;4(6):e005208 - PubMed
  15. J Anesth. 2009;23(1):87-92 - PubMed
  16. Ann Intern Med. 2009 Oct 20;151(8):566-76 - PubMed
  17. Cardiovasc Surg. 1996 Feb;4(1):15-21 - PubMed
  18. BMJ. 2006 Jun 10;332(7554):1365 - PubMed
  19. Circulation. 1994 Nov;90(5 Pt 2):II262-8 - PubMed
  20. Crit Care Med. 1999 Aug;27(8):1454-60 - PubMed
  21. Chest. 1999 Jul;116(1 Suppl):9S-15S - PubMed
  22. Intensive Care Med. 1998 Feb;24(2):172-7 - PubMed
  23. Anesthesiology. 1997 Nov;87(5):1153-63 - PubMed
  24. Curr Opin Anaesthesiol. 2014 Apr;27(2):146-52 - PubMed
  25. Chest. 1992 Nov;102(5):1313-4 - PubMed
  26. J Tehran Heart Cent. 2010 Summer;5(3):128-31 - PubMed
  27. Br J Anaesth. 2004 Sep;93(3):327-32 - PubMed
  28. Acta Anaesthesiol Scand. 2002 Jul;46(6):717-25 - PubMed
  29. J Cardiothorac Surg. 2007 Feb 14;2:11 - PubMed
  30. Anesth Analg. 2004 Oct;99(4):1001-8, table of contents - PubMed
  31. Eur J Cardiothorac Surg. 2002 Aug;22(2):282-6 - PubMed
  32. Crit Care Med. 1973 Jul-Aug;1(4):181-6 - PubMed
  33. Physiol Rev. 2001 Apr;81(2):807-69 - PubMed
  34. Ann Thorac Surg. 1996 Jan;61(1):118-23 - PubMed
  35. Ann Thorac Surg. 1999 Sep;68(3):1107-15 - PubMed
  36. Eur Respir J. 2002 Oct;20(4):946-56 - PubMed
  37. Anesthesiology. 2006 Oct;105(4):689-95 - PubMed
  38. Intensive Care Med. 2005 Sep;31(9):1189-94 - PubMed
  39. Chest. 2009 May;135(5):1252-9 - PubMed
  40. J Card Surg. 1990 Sep;5(3):177-89 - PubMed
  41. Acta Anaesthesiol Scand. 2005 Oct;49(9):1302-10 - PubMed
  42. Ann Thorac Surg. 2003 Aug;76(2):503-7 - PubMed
  43. Ann Thorac Surg. 2000 Apr;69(4):1198-204 - PubMed
  44. Am J Respir Crit Care Med. 2003 Jun 15;167(12):1633-40 - PubMed
  45. Chest. 2002 Apr;121(4):1269-77 - PubMed
  46. J Appl Physiol (1985). 1994 Jan;76(1):166-75 - PubMed
  47. Am J Crit Care. 2004 Sep;13(5):384-93 - PubMed
  48. Anesth Analg. 2008 Oct;107(4):1265-75 - PubMed
  49. Expert Rev Respir Med. 2010 Jun;4(3):373-85 - PubMed
  50. Thorax. 1989 Mar;44(3):209-11 - PubMed
  51. J Thorac Cardiovasc Surg. 2005 Aug;130(2):378-83 - PubMed
  52. Anesthesiology. 1985 Mar;62(3):247-54 - PubMed
  53. Crit Care Med. 2005 Oct;33(10):2253-8 - PubMed
  54. Eur J Cardiothorac Surg. 2000 Jul;18(1):31-7 - PubMed
  55. Rev Bras Cir Cardiovasc. 2012 Dec;27(4):520-8 - PubMed
  56. Chest. 2001 Mar;119(3):884-8 - PubMed
  57. Crit Care Med. 2004 Dec;32(12):2378-84 - PubMed
  58. Thorac Cardiovasc Surg. 1989 Apr;37(2):65-71 - PubMed
  59. J Physiol Pharmacol. 1997 Dec;48(4):537-57 - PubMed
  60. Crit Care Med. 2000 May;28(5):1450-4 - PubMed
  61. Eur J Cardiothorac Surg. 2005 Dec;28(6):889-95 - PubMed
  62. Acta Anaesthesiol Scand. 1998 Nov;42(10 ):1133-8 - PubMed
  63. Crit Care Med. 2001 Jun;29(6):1154-8 - PubMed
  64. Intensive Care Med. 1992;18(6):319-21 - PubMed
  65. Anesthesiol Clin. 2012 Sep;30(3):495-511 - PubMed
  66. Am J Physiol Lung Cell Mol Physiol. 2002 May;282(5):L892-6 - PubMed
  67. Rev Hosp Clin Fac Med Sao Paulo. 2002 Jul-Aug;57(4):135-42 - PubMed
  68. J Cardiothorac Vasc Anesth. 2012 Jun;26(3):448-54 - PubMed
  69. Heart Lung Vessel. 2013;5(3):137-41 - PubMed
  70. J Cardiothorac Vasc Anesth. 2012 Oct;26(5):917-22 - PubMed
  71. Am J Respir Crit Care Med. 2001 Mar;163(4):806-7 - PubMed
  72. Ann Thorac Surg. 2008 Jan;85(1):154-62 - PubMed
  73. Chest. 2010 May;137(5):1203-16 - PubMed
  74. Lancet. 2003 Jan 25;361(9354):332-40 - PubMed
  75. Acta Anaesthesiol Scand. 2000 Jan;44(1):75-81 - PubMed
  76. Anesth Analg. 2000 Sep;91(3):522-7 - PubMed
  77. HSR Proc Intensive Care Cardiovasc Anesth. 2009;1(2):39-47 - PubMed
  78. Anesthesiology. 1998 Jan;88(1):134-42 - PubMed
  79. J Thorac Cardiovasc Surg. 1997 Dec;114(6):1061-9 - PubMed

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